Evidence map›Paper›PMID 34633091›Full record

ArticleJournal of medical virology2022

Transplacental transfer of RSV antibody in Australian First Nations infants.

Nusrat Homaira, Michael Binks, Gregory Walker, Natasha Larter, Katrina Clark, Megan Campbell, Lisa McHugh, Nancy Briggs, Joyce Nyiro, Sacha Stelzer-Braid and 7 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 12 institutions in 3 countries.

Nusrat HomairaDiscipline of Paediatrics, School of Women's and Children's Health, Faculty of Medicine and Health, UNSW, Sydney, New South Wales, Australia.ORCID 0000-0003-3341-7964
Michael BinksMenzies School of Health Research, Darwin, Northern Territory, Australia.
Gregory WalkerPrince of Wales Hospital, Sydney, New South Wales, Australia.
Natasha LarterSydney Children's Hospitals Network, Sydney, New South Wales, Australia.
Katrina ClarkNational Centre for Immunisation Research and Surveillance (NCIRS), Sydney, New South Wales, Australia.
Megan CampbellCentre for Aboriginal Health, New South Wales Health, Sydney, New South Wales, Australia.
Lisa McHughSchool of Public Health, University of Queensland, Brisbane, Queensland, Australia.
Nancy BriggsStats Central, Mark Wainwright Analytical Centre, UNSW, Sydney, New South Wales, Australia.
Joyce NyiroKEMRI-Wellcome Trust Research Programme, Kilifi, Kenya.
Sacha Stelzer-BraidPrince of Wales Hospital, Sydney, New South Wales, Australia.ORCID 0000-0001-6037-9305
Nan HuDiscipline of Paediatrics, School of Women's and Children's Health, Faculty of Medicine and Health, UNSW, Sydney, New South Wales, Australia.
Kristine MacartneyNational Centre for Immunisation Research and Surveillance (NCIRS), Sydney, New South Wales, Australia.
Tom SnellingUniversity of Sydney, Sydney, New South Wales, Australia.
Saad B OmerYale Institute for Global Health, New Haven, Connecticut, USA.
William RawlinsonPrince of Wales Hospital, Sydney, New South Wales, Australia.
Ross AndrewsNational Centre for Immunisation Research and Surveillance (NCIRS), Sydney, New South Wales, Australia.
Adam JaffeDiscipline of Paediatrics, School of Women's and Children's Health, Faculty of Medicine and Health, UNSW, Sydney, New South Wales, Australia.
Prince of Wales Hospital · AUUNSW Sydney · AUNational Centre for Immunisation Research & Surveillance · AUAustralian National University · AUKenya Medical Research Institute · KEMenzies School of Health Research · AUNew South Wales Department of Health · AUNew South Wales Department of Primary Industries · AUQueensland Health · AUSydney Children’s Hospitals Network · AUThe University of Sydney · AUYale New Haven Health System · US

Funding

Wellcome Trust 203077
6 · The paper itself

Abstract

Respiratory syncytial virus (RSV) is the leading cause of acute lower respiratory infection hospitalisations in Aboriginal infants specifically those aged <6 months. Maternally derived RSV antibody (Ab) can protect against severe RSV disease in infancy. However, the efficiency of transplacental transfer of maternal anti-RSV Ab remains unknown in Aboriginal infants. We characterised RSV Ab in Australian First Nations mother-infant pairs (n = 78). We investigated impact of covariates including low birthweight, gestational age (GA), sex of the baby, maternal age and multiparity of the mother on cord to maternal anti-RSV Ab titre ratio (CMTR) using multivariable logistic regression model. All (n = 78) but one infant was born full term (median GA: 39 weeks, interquartile range: 38-40 weeks) and 56% were males. The mean log

Indexed as

Indigenous PeoplesRespiratory Syncytial Virus, HumanRespiratory Syncytial Virus InfectionsAdultAntibodies, ViralAustraliaFemaleHumansInfantInfant, NewbornLogistic ModelsMaleMothersMultivariate AnalysisYoung AdultAntibodies, Viralindigenous infantsRSV antibodytransplacental transfer

Identifiers

PMID34633091
PMCPMC7613379
OpenAlexW3205927621

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.