Evidence map›Paper›PMID 34632981›Full record

ArticleeLife2021

A beta-glucosidase of an insect herbivore determines both toxicity and deterrence of a dandelion defense metabolite.

Meret Huber, Thomas Roder, Sandra Irmisch, Alexander Riedel, Saskia Gablenz, Julia Fricke, Peter Rahfeld, Michael Reichelt, Christian Paetz, Nicole Liechti and 7 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Plants (Basel, Switzerland) · 2025
    Article
  3. Article
  4. Plant sesquiterpene lactones.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  5. Pharmaceuticals (Basel, Switzerland) · 2024
    Article
  6. Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 3 institutions in 4 countries.

Meret HuberInstitute of Plant Biology and Biotechnology, University of Muenster, Muenster, Germany.ORCID 0000-0002-8708-394X
Thomas RoderInstitute of Plant Sciences, University of Bern, Bern, Switzerland.ORCID 0000-0002-6642-6288
Sandra IrmischDepartment of Biochemistry, Max-Planck Institute for Chemical Ecology, Jena, Germany.
Alexander RiedelDepartment of Biochemistry, Max-Planck Institute for Chemical Ecology, Jena, Germany.
Saskia GablenzDepartment of Biochemistry, Max-Planck Institute for Chemical Ecology, Jena, Germany.
Julia FrickeInstitute of Plant Sciences, University of Bern, Bern, Switzerland.
Peter RahfeldDepartment of Bioorganic Chemistry, Max-Planck Institute for Chemical Ecology, Jena, Germany.
Michael ReicheltDepartment of Biochemistry, Max-Planck Institute for Chemical Ecology, Jena, Germany.ORCID 0000-0002-6691-6500
Christian PaetzResearch group Biosynthesis/NMR, Max-Planck Institute for Chemical Ecology, Jena, Germany.
Nicole LiechtiInstitute of Plant Sciences, University of Bern, Bern, Switzerland.
Lingfei HuInstitute of Plant Sciences, University of Bern, Bern, Switzerland.
Zoe BontInstitute of Plant Sciences, University of Bern, Bern, Switzerland.
Ye MengInstitute of Plant Sciences, University of Bern, Bern, Switzerland.
Wei HuangInstitute of Plant Sciences, University of Bern, Bern, Switzerland.
Christelle Am RobertInstitute of Plant Sciences, University of Bern, Bern, Switzerland.ORCID 0000-0003-3415-2371
Jonathan GershenzonDepartment of Biochemistry, Max-Planck Institute for Chemical Ecology, Jena, Germany.ORCID 0000-0002-1812-1551
Matthias ErbInstitute of Plant Sciences, University of Bern, Bern, Switzerland.ORCID 0000-0002-4446-9834
University of Bern · CHMax Planck Institute for Chemical Ecology · DEInstitute of Plant Biology and Biotechnology · KZ

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gut enzymes can metabolize plant defense compounds and thereby affect the growth and fitness of insect herbivores. Whether these enzymes also influence feeding preference is largely unknown. We studied the metabolization of taraxinic acid β-D-glucopyranosyl ester (TA-G), a sesquiterpene lactone of the common dandelion (

Indexed as

HerbivoryAnimalsbeta-GalactosidaseColeopteraDigestionGlucosidesGlutathioneHydrolysisInactivation, MetabolicInsect ProteinsLactonesLarvaSecondary MetabolismSesquiterpenesTaraxacumbeta-GalactosidaseGlucosidesGlutathioneInsect ProteinsLactonesSesquiterpenestaraxinic acid glucopyranosyl esterecologyMelolontha melolonthaplant defenseroot herbivoresesquiterpene lactoneTaraxacum officinaleβ-glucosidase

Identifiers

PMID34632981
PMCPMC8504966
OpenAlexW3207455296

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.