Evidence map›Paper›PMID 34632957›Full record

ArticleGut microbes

Colonic expression of

Adam Edwinson, Lu Yang, Jun Chen, Madhusudan Grover

Open access · goldAbstract read
In one paragraph

Article in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.4field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
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  3. Significant Increase inGastro hep advances · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Adam EdwinsonDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Lu YangDepartment of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA.
Jun ChenDepartment of Biomedical Statistics and Informatics, Mayo Clinic, Rochester, MN, USA.
Madhusudan GroverDivision of Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Florida · USWinnMed · US

Funding

PILOT AND FEASIBILTY PROGRAMP30DK084567 · NIDDK · MAYO CLINIC ROCHESTER · PI Nicholas F. LaRusso · 2009 to 2026
$22.2M
"Barrier function alterations in post-infectious irritable bowel syndrome"K23DK103911 · NIDDK · MAYO CLINIC ROCHESTER · PI GROVER, MADHUSUDAN · 2015 to 2019
$804k
Mechanisms of barrier dysfunction in post-infection irritable bowel syndromeR03DK120745 · NIDDK · MAYO CLINIC ROCHESTER · PI GROVER, MADHUSUDAN · 2019 to 2020
$239k
NIDDK NIH HHS K23 DK103911NIDDK NIH HHS P30 DK084567NIDDK NIH HHS R03 DK120745
6 · The paper itself

Abstract

Infection with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) is responsible for the COVID-19 pandemic. Angiotensin-converting enzyme 2 (

Indexed as

Gastrointestinal MicrobiomeAngiotensin-Converting Enzyme 2AnimalsColonDysbiosisGene Expression RegulationGerm-Free LifeHumansInflammatory Bowel DiseasesMiceReceptors, VirusSARS-CoV-2ACE2 protein, humanAngiotensin-Converting Enzyme 2Receptors, ViruscoronavirusDysbiosisgerm-free miceintestinal

Identifiers

PMID34632957
PMCPMC8510562
OpenAlexW3207771124

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.