Evidence map›Paper›PMID 34632932›Full record

ArticleBioengineered2021

Long non-coding RNA growth arrest specific transcript 5 acting as a sponge of MicroRNA-188-5p to regulate SMAD family member 2 expression promotes myocardial ischemia-reperfusion injury.

Jin Xu, Dong Yu, Xiaolu Bai, Peng Zhang

Open access · goldAbstract read
In one paragraph

Article in Bioengineered, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 4 institutions in 1 country.

Jin XuDepartment of Anesthesiology, Shanghai East Hospital, Tongji University School of Medicine, Shanghai City, China.
Dong YuDepartment of Cardiology, Minhang Hospital of Zhongshan Hospital Affiliated to Fudan University (Central Hospital, Minhang District, Shanghai), Shanghai City, China.
Xiaolu BaiDepartment of Cardiology, Minhang Hospital of Zhongshan Hospital Affiliated to Fudan University (Central Hospital, Minhang District, Shanghai), Shanghai City, China.
Peng ZhangDepartment of Cardiology, Minhang Hospital of Zhongshan Hospital Affiliated to Fudan University (Central Hospital, Minhang District, Shanghai), Shanghai City, China.
Fudan University · CNMinhang District Central Hospital · CNShanghai East Hospital · CNZhongshan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The purpose of this work is to probe into the potential role of long non-coding RNA growth arrest specific transcript 5 (lncGAS5)/ microRNA (miR)-188-5p/SMAD2 axis in MIRI. Through ligating the left anterior descending (LAD) coronary artery, MIRI animal model and hypoxia/reoxygenation (H/R) myocardial injury model

Indexed as

Myocardial Reperfusion InjuryAnimalsCells, CulturedFemaleHumansMaleMiceMice, Inbred C57BLMicroRNAsMiddle AgedMyocytes, CardiacRNA, Small NucleolarSmad2 Proteingrowth arrest specific transcript 5MicroRNAsMIRN188 microRNA, humanRNA, Small NucleolarSmad2 ProteinSMAD2 protein, humanLong non-coding RNA growth arrest specific transcript 5microRNA-188-pmyocardial ischemia-reperfusion injuryNF-ΚBsmad2

Identifiers

PMID34632932
PMCPMC8806717
OpenAlexW3206491645

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.