Evidence map›Paper›PMID 34632855›Full record

ArticleExperimental biology and medicine (Maywood, N.J.)2022

Combining contrast-enhanced ultrasound and blood cell analysis to improve diagnostic accuracy of plasma cell mastitis.

Yan Zheng, Lin Wang, Xiu Han, Lin Shen, Chen Ling, Zhongping Qian, Lin Zhu, Fenglin Dong, Qingzhen Han

Open access · greenAbstract read
In one paragraph

Article in Experimental biology and medicine (Maywood, N.J.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
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  5. Article
  6. Research Progress of Plasma Cell Mastitis.Immunity, inflammation and disease · 2025
    Review
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  8. Review
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Yan ZhengThe First Affiliated Hospital of Soochow University, Suzhou 215000, China.
Lin WangCenter of Clinical Laboratory, Dushu Lake Hospital Affiliated to Soochow University, Suzhou 215000, China.
Xiu HanCenter of Clinical Laboratory, Dushu Lake Hospital Affiliated to Soochow University, Suzhou 215000, China.
Lin ShenSuzhou Municipal Hospital, Suzhou 215000, China.
Chen LingThe First Affiliated Hospital of Soochow University, Suzhou 215000, China.
Zhongping QianThe First Affiliated Hospital of Soochow University, Suzhou 215000, China.
Lin ZhuThe First Affiliated Hospital of Soochow University, Suzhou 215000, China.
Fenglin DongThe First Affiliated Hospital of Soochow University, Suzhou 215000, China.
Qingzhen HanCenter of Clinical Laboratory, Dushu Lake Hospital Affiliated to Soochow University, Suzhou 215000, China.ORCID 0000-0001-7373-891X
Soochow University · CNSuzhou Municipal Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Plasma cell mastitis is a benign suppurative disease of the breast, lack of specific clinical manifestations, which is easy to be misdiagnosed and mistreated, often confused with mastitis, breast cancer (BC), and other diseases. Thus, we aimed to establish a combined model of promoting diagnostic accuracy of plasma cell mastitis by contrast-enhanced ultrasound (CEUS) patterns and routine blood cell analysis. Eighty-eight plasma cell mastitis, 91 breast cancer, and 152 other benign breast diseases' patients grouped according to pathological diagnosis underwent CEUS and blood cell analysis examination; 100 healthy female donors were involved. All the plasma cell mastitis and breast cancer patients presented hyperenhancement of CEUS breast lesions compared with others. The majority of plasma cell mastitis (65/88) showed perfusion defect of CEUS patterns with smooth edge (56/65) and multiple lesions (49/65); in contrast, fewer breast cancer patients (30/91) displayed perfusion defect. White blood cell count (WBC), neutrophils, and neutrophils/lymphocytes ratio of blood cell analysis in plasma cell mastitis patients increased significantly compared with other patients (

Indexed as

Breast NeoplasmsPlasma CellsAdultAgedAged, 80 and overContrast MediaDiagnosis, DifferentialFemaleHumansMastitisMiddle AgedRetrospective StudiesUltrasonographyContrast Mediabreast carcinomacontrast-enhanced ultrasounddifferential diagnosisinflammationPlasma cell mastitiswhite blood cell count

Identifiers

PMID34632855
PMCPMC8777476
OpenAlexW3205874372

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.