Evidence map›Paper›PMID 34632823›Full record

Observational studyJournal of diabetes science and technology2023

Patient Demographics and Clinical Outcomes Among Type 1 Diabetes Patients Using Continuous Glucose Monitors: Data From T1D Exchange Real-World Observational Study.

Daniel J DeSalvo, Nudrat Noor, Cicilyn Xie, Sarah D Corathers, Shideh Majidi, Ryan J McDonough, Sarit Polsky, Roberto Izquierdo, Nicole Rioles, Ruth Weinstock and 5 more

Open access · greenAbstract readObservational Study
In one paragraph

Observational study in Journal of diabetes science and technology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 2 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 2 syntheses or guidelines pooled it, 108 citations in OpenAlex.

  1. Real-World Evidence of Automated Insulin Delivery System Use.Diabetes technology & therapeutics · 2024
    Pooled it
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  17. The Urgent Need for Breakthrough Therapies and a World Without Type 1 Diabetes.Diabetes therapy : research, treatment and education of diabetes and related disorders · 2025
    Article
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  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 11 institutions in 1 country.

Daniel J DeSalvoTexas Children's Hospital, Baylor College of Medicine, Houston, TX, USA.
Nudrat NoorT1D Exchange, Boston, MA, USA.ORCID 0000-0003-0400-7835
Cicilyn XiePaul L. Foster School of Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, TX, USA.
Sarah D CorathersCincinnati Children's Hospital Medical Center, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
Shideh MajidiBarbara Davis Center for Diabetes, Aurora, CO, USA.
Ryan J McDonoughChildren's Mercy Kansas City, Kansas City, MO, USA.
Sarit PolskyBarbara Davis Center for Diabetes, Aurora, CO, USA.
Roberto IzquierdoSUNY Upstate Medical University, Syracuse, NY, USA.
Nicole RiolesT1D Exchange, Boston, MA, USA.
Ruth WeinstockSUNY Upstate Medical University, Syracuse, NY, USA.ORCID 0000-0001-5859-5666
Kathryn ObrynbaNationwide Children's Hospital, Columbus, OH, USA.
Alissa RobertsSeattle Children's Hospital, Seattle, WA, USA.ORCID 0000-0002-0221-6273
Francesco VendrameSchool of Medicine, University of Miami Miller, Miami, FL, USA.
Janine SanchezSchool of Medicine, University of Miami Miller, Miami, FL, USA.
Osagie EbekozienT1D Exchange, Boston, MA, USA.ORCID 0000-0002-8473-249X
Sansum Diabetes Research Institute · USSUNY Upstate Medical University · UST1D Exchange · USUniversity of Miami · USBaylor College of Medicine · USChildren's Mercy Hospital · USCincinnati Children's Hospital Medical Center · USNationwide Children's Hospital · USSeattle Children's Hospital · USTexas Tech University · USUniversity of Mississippi · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe benefits of Continuous Glucose Monitoring (CGM) on glycemic management have been demonstrated in numerous studies; however, widespread uptake remians limited. The aim of this study was to provide real-world evidence of patient attributes and clinical outcomes associated with CGM use across clinics in the U.S. based T1D Exchange Quality Improvement (T1DX-QI) Collaborative.

methodWe examined electronic Health Record data from eight endocrinology clinics participating in the T1DX-QI Collaborative during the years 2017-2019.

resultsAmong 11,469 type 1 diabetes patients, 48% were CGM users. CGM use varied by race/ethnicity with Non-Hispanic Whites having higher rates of CGM use (50%) compared to Non-Hispanic Blacks (18%) or Hispanics (38%). Patients with private insurance were more likely to use CGM (57.2%) than those with public insurance (33.3%) including Medicaid or Medicare. CGM users had lower median HbA1c (7.7%) compared to nonusers (8.4%). Rates of diabetic ketoacidosis (DKA) and severe hypoglycemia were significantly higher in nonusers compared to CGM users.

conclusionIn this real-world study of patients in the T1DX-QI Collaborative, CGM users had better glycemic control and lower rates of DKA and severe hypoglycemia (SH) events, compared to nonusers; however, there were significant sociodemographic disparities in CGM use. Quality improvement and advocacy measures to promote widespread and equitable CGM uptake have the potential to improve clinical outcomes.

Indexed as

Diabetes Mellitus, Type 1Diabetic KetoacidosisHypoglycemiaAgedBlood GlucoseBlood Glucose Self-MonitoringDemographyHumansMedicareUnited StatesBlood Glucosecontinuous glucose monitoringdiabetes mellitusdiabetic ketoacidosishemoglobin A1csevere hypoglycemiaType 1

Identifiers

PMID34632823
PMCPMC10012384
OpenAlexW3207603420

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.