Evidence map›Paper›PMID 34632795›Full record

ArticleJournal of the American Heart Association2021

Sex Differences in the Utilization and Outcomes of Cardiac Valve Replacement Surgery for Infective Endocarditis: Insights From the National Inpatient Sample.

Agam Bansal, Paul C Cremer, Wael A Jaber, Penelope Rampersad, Venu Menon

Open access · goldAbstract read
In one paragraph

Article in Journal of the American Heart Association, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 39 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Review
  5. Article
  6. Surgery inJournal of clinical medicine · 2025
    Article
  7. Article
  8. Article
  9. Observational
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. IDCases · 2024
    Article
  16. Article
  17. Review
  18. Sex Differences in the Outcomes of Degenerative Mitral Valve Repair.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Agam BansalDepartment of Cardiovascular Medicine Heart and Vascular Institute Cleveland Clinic Foundation Cleveland OH.ORCID 0000-0002-6404-7436
Paul C CremerDepartment of Cardiovascular Medicine Heart and Vascular Institute Cleveland Clinic Foundation Cleveland OH.ORCID 0000-0002-0794-3306
Wael A JaberDepartment of Cardiovascular Medicine Heart and Vascular Institute Cleveland Clinic Foundation Cleveland OH.ORCID 0000-0001-5642-2112
Penelope RampersadDepartment of Cardiovascular Medicine Heart and Vascular Institute Cleveland Clinic Foundation Cleveland OH.ORCID 0000-0003-4829-9059
Venu MenonDepartment of Cardiovascular Medicine Heart and Vascular Institute Cleveland Clinic Foundation Cleveland OH.ORCID 0000-0003-4410-2677
Cleveland Clinic · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background The data on the differential impact of sex on the utilization and outcomes of valve replacement surgery for infective endocarditis are limited to single-center and small sample size patient population. Methods and Results We utilized the National Inpatient Sample database to identify patients with a discharge diagnosis of infective endocarditis from 2004 to 2015 to assess differences in the characteristics and clinical outcomes of patients hospitalized with infective endocarditis stratified by sex. We also evaluated trends in utilization of cardiac valve replacement and individual valve replacement surgeries in women versus men over a 12-year period, and compared in-hospital mortality after surgical treatment in women versus men. A total of 81 942 patients were hospitalized with a primary diagnosis of infective endocarditis from January 2004 to September 2015, of whom 44.31% were women. Women were less likely to undergo overall cardiac valve replacement (6.92% versus 12.12%), aortic valve replacement (3.32% versus 8.46%), mitral valve replacement (4.60% versus 5.57%), and combined aortic and mitral valve replacement (0.85% versus 1.81%) but had similar in-hospital mortality rates. From 2004 to 2015, the overall rates of cardiac valve replacement increased from 11.76% to 13.96% in men and 6.34% to 9.26% in women and in-hospital mortality declined in both men and women. Among the patients undergoing valve replacement surgery, in-hospital mortality was higher in women (9.94% versus 6.99%,

Indexed as

EndocarditisEndocarditis, BacterialHeart Valve Prosthesis ImplantationAortic ValveFemaleHumansInpatientsMaleSex Characteristicsinfective endocarditissex differencesunderutilizationvalve replacement

Identifiers

PMID34632795
PMCPMC8751869
OpenAlexW3205289243

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.