Evidence map›Paper›PMID 34632569›Full record

ArticleBritish journal of haematology2022

Clinical significance of the immunoglobulin G heavy-chain repertoire in peripheral blood mononuclear cells of adult T-cell leukaemia-lymphoma patients receiving mogamulizumab.

Kisato Nosaka, Shigeru Kusumoto, Nobuaki Nakano, Ilseung Choi, Makoto Yoshimitsu, Yoshitaka Imaizumi, Michihiro Hidaka, Hidenori Sasaki, Junya Makiyama, Eiichi Ohtsuka and 14 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in British journal of haematology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 49% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors at 15 institutions in 1 country.

Kisato NosakaCancer Center, Kumamoto University Hospital, Kumamoto, Japan.ORCID 0000-0001-6682-2451
Shigeru KusumotoDepartment of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Nobuaki NakanoDepartment of Hematology, Imamura General Hospital, Kagoshima, Japan.ORCID 0000-0001-9826-7616
Ilseung ChoiDepartment of Hematology, National Hospital Organization Kyushu Cancer Centre Hospital, Fukuoka, Japan.
Makoto YoshimitsuDepartment of Hematology and Rheumatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshiam, Japan.ORCID 0000-0002-5935-0385
Yoshitaka ImaizumiDepartment of Hematology, Nagasaki University Hospital, Nagasaki, Japan.
Michihiro HidakaDepartment of Hematology, National Hospital Organization Kumamoto Medical Center, Kumamoto, Japan.
Hidenori SasakiDivision of Medical Oncology, Department of Medicine, Hematology, and Infectious Diseases, Fukuoka University Hospital, Fukuoka, Japan.
Junya MakiyamaDepartment of Hematology, Sasebo City General Hospital, Sasebo, Japan.
Eiichi OhtsukaDepartment of Hematology, Oita Prefectural Hospital, Oita, Japan.
Tatsuro JoDepartment of Hematology, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Japan.
Masao OgataDepartment of Hematology, Oita University Hospital, Oita, Japan.
Asahi ItoDepartment of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Kentaro YonekuraDepartment of Dermatology, Imamura General Hospital, Kagoshima, Japan.
Hiro TatetsuDepartment of Hematology, Kumamoto University Hospital, Kumamoto, Japan.
Takeharu KatoDepartment of Hematology, Nagasaki University Hospital, Nagasaki, Japan.
Toshiro KawakitaDepartment of Hematology, National Hospital Organization Kumamoto Medical Center, Kumamoto, Japan.
Youko SuehiroDepartment of Hematology, National Hospital Organization Kyushu Cancer Centre Hospital, Fukuoka, Japan.
Kenji IshitsukaDepartment of Hematology and Rheumatology, Kagoshima University Graduate School of Medical and Dental Sciences, Kagoshiam, Japan.
Shinsuke IidaDepartment of Hematology and Oncology, Nagoya City University Graduate School of Medical Sciences, Nagoya, Japan.
Takaji MatsutaniOsaka laboratory, Repertoire Genesis Incorporation, Ibaraki, Osaka, Japan.
Atae UtsunomiyaDepartment of Hematology, Imamura General Hospital, Kagoshima, Japan.ORCID 0000-0002-8843-406X
Ryuzo UedaDepartment of Tumor Immunology, Aichi Medical University School of Medicine, Nagakute, Japan.
Takashi IshidaDepartment of Immunology, Nagoya University Graduate School of Medicine, Nagoya, Japan.ORCID 0000-0002-1060-0777
Imamura Hospital · JPNagoya City University · JPKagoshima University · JPKumamoto Medical Center · JPKumamoto University Hospital · JPNagasaki University Hospital · JPNational Hospital Organization Kyushu Cancer Center · JPAichi Medical University · JPFukuoka University Hospital · JPGenesis Research Institute · JPJapanese Red Cross Society, Japan · JPNagoya University · JPOita Prefectural Hospital · JPOita University Hospital · JPSasebo City General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

'Monitoring of immune responses following mogamulizumab-containing treatment in patients with adult T-cell leukaemia-lymphoma (ATL)' (MIMOGA) is a multicentre prospective clinical study (UMIN000008696). In the MIMOGA study, we found that a lower percentage of CD2

Indexed as

Biomarkers, TumorCirculating Tumor DNAAdultAgedAged, 80 and overAntibodies, Monoclonal, HumanizedAntineoplastic Agents, ImmunologicalFemaleGenetic VariationHumansImmunoglobulin GImmunoglobulin Heavy ChainsLeukemia-Lymphoma, Adult T-CellLeukocytes, MononuclearMaleMiddle AgedAntibodies, Monoclonal, HumanizedAntineoplastic Agents, ImmunologicalBiomarkers, TumorCirculating Tumor DNAImmunoglobulin GImmunoglobulin Heavy Chainsmogamulizumabadult T-cell leukaemia-lymphomaimmunoglobulin G B-cell diversitymogamulizumab

Identifiers

PMID34632569
PMCPMC9292985
OpenAlexW3206632503

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.