Evidence map›Paper›PMID 34632541›Full record

ReviewJournal of ophthalmic inflammation and infection2021

Intraocular therapy in noninfectious uveitis.

Rocco Luigi Modugno, Ilaria Testi, Carlos Pavesio

Open access · goldAbstract readReview
In one paragraph

Review in Journal of ophthalmic inflammation and infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Corticosteroid implants for chronic non-infectious uveitis.The Cochrane database of systematic reviews · 2023
    Pooled it
  2. Article
  3. Review
  4. Review
  5. Corticosteroid implants for chronic non-infectious uveitis.The Cochrane database of systematic reviews · 2023
    Review
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Rocco Luigi ModugnoDepartment of Neuroscience, Ophthalmology Unit, University of Padua, Padua, Italy.
Ilaria TestiMoorfields Eye Hospital, National Health Service Foundation Trust, 162 City Rd, Old Street, London, EC1V 2PD, UK.
Carlos PavesioMoorfields Eye Hospital, National Health Service Foundation Trust, 162 City Rd, Old Street, London, EC1V 2PD, UK. c.pavesio@nhs.net.
Moorfields Eye Hospital NHS Foundation Trust · GBUniversity of Padua · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic corticosteroids and immunosuppressant agents are the mainstay of therapy for non-infectious uveitis (NIU). However, the risks associated with systemic administration and the need of delivering an effective and safe anti-inflammatory treatment targeted to the site of inflammation have prompt the use of local therapy in the management of NIU. This review will analyse the different local treatment options available, including corticosteroids, anti-vascular endothelial growth factor (VEGF), methotrexate and the recent biologics.

Indexed as

Anti-tumor necrosis factor (TNF) αAnti-vascular endothelial growth factor (VEGF)BiologicsCorticosteroidsImmunosuppressive agentsIntravitrealLocal therapyMethotrexateNon-infectious uveitis

Identifiers

PMID34632541
PMCPMC8502718
OpenAlexW3205110195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.