Evidence map›Paper›PMID 34632523›Full record

ArticleCardiovascular and interventional radiology2022

Minimally Invasive Treatment for Unicameral Bone Cysts with Chemical Sclerosis and Bone Graft Substitute: A Preliminary Report.

Shankar Rajeswaran, Ali Khan, Jonathan D Samet, James Donaldson, Samer Attar, Terrance Peabody, Jared Green

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Article in Cardiovascular and interventional radiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Musculoskeletal Intervention in Children: An Update.Cardiovascular and interventional radiology · 2026
    Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shankar RajeswaranLurie Children's Hospital of Chicago, 225 E Chicago, Chicago, IL, 60611, USA.
Ali KhanNorthwestern University Feinberg School of Medicine, 420 E Superior St, Chicago, IL, 60611, USA. ali.khan1@northwestern.edu.ORCID http://orcid.org/0000-0002-1709-7449
Jonathan D SametLurie Children's Hospital of Chicago, 225 E Chicago, Chicago, IL, 60611, USA.
James DonaldsonLurie Children's Hospital of Chicago, 225 E Chicago, Chicago, IL, 60611, USA.
Samer AttarLurie Children's Hospital of Chicago, 225 E Chicago, Chicago, IL, 60611, USA.
Terrance PeabodyLurie Children's Hospital of Chicago, 225 E Chicago, Chicago, IL, 60611, USA.
Jared GreenLurie Children's Hospital of Chicago, 225 E Chicago, Chicago, IL, 60611, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeUnicameral bone cysts (UBCs) are benign lesions that primarily occur in childhood and can present with pain, pathologic fracture and growth disturbances. Existing treatment approaches for the management of UBCs are highly variable and recurrence is not uncommon. This study seeks to evaluate near-term outcomes of an image-guided, minimally invasive combination of chemical sclerotherapy and synthetic grafting as a novel outpatient management treatment option for UBCs. MATERIALS AND

methodsRetrospective evaluation from August 2018 to July 2020 of fourteen pediatric patients, ages 5-14 years, undergoing treatment for a UBC, at a single institution. All UBCs were treated in a single, minimally invasive, image-guided procedure using percutaneous needle access into the UBC followed by chemical sclerotherapy and injection of regenerative synthetic graft. Patients were followed clinically and with serial radiographs to evaluate for healing and complications, with an average follow-up of 13.7 months. Descriptive statistics were performed.

resultsTwelve of 14 (85.7%) patients showed Modified Neer classification class 1 or 2 healed cysts at their most recent follow-up. There were two recurrences. All patients were pain-free and returned to normal physical activity on average within 2.0 months, and all patients with healed cysts remained asymptomatic at the most recent follow-up. There were no complications related to the procedures.

conclusionsImage-guided chemical sclerosis and bone grafting is a minimally invasive treatment option for unicameral bone cysts and compares favorably to other existing treatment options. The preliminary findings of this technique are promising as an alternative management option for UBCs.

Indexed as

Bone CystsBone SubstitutesFractures, SpontaneousAdolescentChildChild, PreschoolHumansRetrospective StudiesSclerosisBone SubstitutesBone graftingSclersosisUBCUnicameral bone cysts

Identifiers

PMID34632523

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.