Evidence map›Paper›PMID 34632503›Full record

Trial reportInteractive cardiovascular and thoracic surgery2022

Actual incidence of cerebral infarction after thoracic endovascular aortic repair: a magnetic resonance imaging study.

Sohsyu Kotani, Yoshito Inoue, Naohiko Oki, Hideki Yashiro, Takashi Hachiya

Open access · hybridAbstract readClinical Trial
In one paragraph

Trial report in Interactive cardiovascular and thoracic surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. CT-Derived Aortic Plaque Characteristics Predict MRI-Detected Silent Cerebral Infarction after Total Aortic Arch Replacement.Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Sohsyu KotaniDepartment of Cardiovascular Surgery, Tokai University School of Medicine, Kanagawa, Japan.ORCID 0000-0001-5949-9641
Yoshito InoueDepartment of Cardiovascular Surgery, Tokyo Dental College Ichikawa General Hospital, Chiba, Japan.
Naohiko OkiDepartment of Cardiovascular Surgery, Hiratsuka City Hospital, Kanagawa, Japan.
Hideki YashiroDepartment of Radiology, Hiratsuka City Hospital, Kanagawa, Japan.
Takashi HachiyaDepartment of Cardiovascular Surgery, Saiseikai Yokohamashi Tobu Hospital, Kanagawa, Japan.
Hiratsuka City Hospital · JPTokai University · JPTokyo Dental College Ichikawa General Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe actual incidence of cerebral infarction (CI), including asymptomatic infarction, owing to thoracic endovascular aortic repair (TEVAR) has not been reported in detail. This study was performed to investigate the incidence of post-TEVAR CI by using diffusion-weighted magnetic resonance imaging (DW-MRI) and to determine the risk factors for both symptomatic and asymptomatic CI.

methodsWe examined 64 patients undergoing TEVAR at our institute between April 2017 and November 2020. Aortic atheroma was graded from 1 to 5 by preoperative computed tomography. Cerebral DW-MRIs were conducted 2 days after the procedure to diagnose postoperative CI.

resultsA total of 44 new foci were detected by post-interventional cerebral DW-MRI in 22 patients (34.4%). Only one patient developed a symptomatic stroke (1.6%), and TEVAR was successfully completed in all cases. Debranching of the aortic arch and left subclavian artery occlusion with a vascular plug was performed in 19 (29.7%) and 12 (18.8%) patients, respectively. The number of patients with proximal landing zones 0-2 was significantly higher in the CI group than in the non-CI group (68.2% vs 11.9%; P < 0.001). The following risk factors were identified for asymptomatic CI: aortic arch debranching (P < 0.001), left subclavian artery occlusion (P = 0.001) and grade 4/5 aortic arch atheroma (P = 0.048).

conclusionsOver one-third of the patients examined by cerebral DW-MRI after TEVAR were diagnosed with CI. High-grade atheroma and TEVAR landing in zone 0-2 were found to be positively associated with asymptomatic CI. CLINICAL

trial registration02-014.

Indexed as

Aortic Aneurysm, ThoracicBlood Vessel Prosthesis ImplantationEndovascular ProceduresAorta, ThoracicBlood Vessel ProsthesisCerebral InfarctionDiffusion Magnetic Resonance ImagingHumansIncidenceRetrospective StudiesRisk FactorsTreatment OutcomeCerebral infarctionDiffusion-weighted magnetic resonance imagingThoracic endovascular aortic repair

Identifiers

PMID34632503
PMCPMC8766213
OpenAlexW3206108773

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.