Evidence map›Paper›PMID 34632479›Full record

ArticleAlcohol and alcoholism (Oxford, Oxfordshire)2022

Unique and Transdiagnostic Dimensions of Reward Functioning in Attention-Deficit/Hyperactivity Disorder and Alcohol Use Disorder Symptoms.

Lauren E Oddo, Samuel F Acuff, Melanie B Arenson, Assaf Oshri, Andrea Chronis-Tuscano, James MacKillop, James G Murphy

Abstract read
In one paragraph

Article in Alcohol and alcoholism (Oxford, Oxfordshire), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Substance use negatively impacts change in reinforcement during the year following substance use treatment.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lauren E OddoDepartment of Psychology, University of Maryland, 4094 Campus Dr, College Park, MD 20742, USA.ORCID 0000-0003-0773-9644
Samuel F AcuffDepartment of Psychology, University of Memphis, 400 Innovation Dr, Memphis, TN 38111, USA.
Melanie B ArensonDepartment of Psychology, University of Maryland, 4094 Campus Dr, College Park, MD 20742, USA.
Assaf OshriDepartment of Human Development and Family Science, University of Georgia, 305 Sanford Dr. Athens, GA 30602, USA.
Andrea Chronis-TuscanoDepartment of Psychology, University of Maryland, 4094 Campus Dr, College Park, MD 20742, USA.
James MacKillopDepartment of Psychiatry and Behavioural Neurosciences, McMaster University, 1280 Main Street West | Hamilton, Ontario L8S4L8 Canada.
James G MurphyDepartment of Psychology, University of Memphis, 400 Innovation Dr, Memphis, TN 38111, USA.

Funding

The role of religiosity, socioeconomic status and the relationship between behavioral economic variables as mediators of negative alcohol-related consequences in African American emerging adultsR01AA024930 · NIAAA · UNIVERSITY OF MEMPHIS · PI MACKILLOP, JAMES, MURPHY, JAMES G. · 2017 to 2021
$1.6M
A Behavioral Economics Approach to Understanding the Association between ADHD and Alcohol Problems in CollegeF31AA027937 · NIAAA · UNIV OF MARYLAND, COLLEGE PARK · PI ODDO, LAUREN ELIZABETH · 2019 to 2021
$130k
Integration of Electrophysiological and Behavioral Economic Models of Reward Among Heavy Drinking Emerging AdultsF31AA027140 · NIAAA · UNIVERSITY OF MEMPHIS · PI ACUFF, SAMUEL FISHER · 2019 to 2021
$109k
NIAAA NIH HHS F31 AA027140NIAAA NIH HHS F31 AA027937NIAAA NIH HHS R01 AA024930
6 · The paper itself

Abstract

aimsContemporary theories of attention-deficit/hyperactivity disorder (ADHD) and alcohol use disorder (AUD) emphasize core dysfunctions in reward-related processes and behaviors as pathognomonic characteristics. However, to date, it is unclear which domains of reward functioning are unique to ADHD versus AUD symptom dimensions, and which represent underlying shared correlates.

methodsThe current study employed secondary data analyses from a large community sample of emerging adults (N = 602; 57.3% female) and novel transdiagnostic modeling (i.e. bi-factor confirmatory factor analyses and structural equation modeling) of ADHD, AUD and shared symptom dimensions to identify unique and common reward-related dimensions: environmental suppressors, reward probability, hedonic capacity, proportionate substance-related reinforcement and delay discounting.

resultsThe presence of environmental suppressors was the only reward-related construct that correlated with the underlying ADHD-AUD shared dimension. The AUD symptom dimension was uniquely associated with proportionate substance-related reinforcement, whereas the ADHD symptom dimension was uniquely associated with limited reward probability. No significant associations were found for delay discounting or hedonic capacity.

conclusionsThese novel findings highlight specific aspects of reward-related functioning in ADHD, AUD and shared symptom dimensions. In so doing, this work meaningfully advances theoretical conceptualizations of these two commonly co-occurring presentations and suggests future directions for research on transdiagnostic correlates. Future longitudinal studies should include clinical samples with diagnoses of AUD and ADHD to further identify underlying correlates over time.

Indexed as

AlcoholismAttention Deficit Disorder with HyperactivityAdultAlcohol DrinkingFactor Analysis, StatisticalFemaleHumansMaleReward

Identifiers

PMID34632479
PMCPMC9270991

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.