Evidence map›Paper›PMID 34632453›Full record

ArticleJournal of the American College of Emergency Physicians open2021

Hyperkalemia management in the emergency department: An expert panel consensus.

Zubaid Rafique, Frank Peacock, Terra Armstead, Jason J Bischof, Joanna Hudson, Matthew R Weir, James Neuenschwander

Abstract read
In one paragraph

Article in Journal of the American College of Emergency Physicians open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Guideline
  2. Trial
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Hyperkalemia or Not? A Diagnostic Pitfall in the Emergency Department.The western journal of emergency medicine · 2025
    Article
  11. Observational
  12. Management of hyperkalemia: Expert consensus from Kuwait - a Modified Delphi Approach.International journal of nephrology and renovascular disease · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Treatment of hyperkalemic emergencies.World journal of emergency medicine · 2022
    Article
  17. Hyperkalemia management in the emergency department: An expert panel consensus.Journal of the American College of Emergency Physicians open · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Zubaid RafiqueBaylor College of Medicine Department of Emergency Medicine Ben Taub General Hospital Houston Texas USA.ORCID https://orcid.org/0000-0002-4176-5988
Frank PeacockBaylor College of Medicine Department of Emergency Medicine Ben Taub General Hospital Houston Texas USA.
Terra ArmsteadMuskingum University New Concord Ohio USA.
Jason J BischofThe Ohio State University Department of Emergency Medicine Columbus Ohio USA.
Joanna HudsonThe University of Tennessee Health Science Center Departments of Clinical Pharmacy and Translational Science & Medicine (Nephrology) Memphis Tennessee USA.
Matthew R WeirDivision of Nephrology Department of Medicine University of Maryland School of Medicine Baltimore Maryland USA.
James NeuenschwanderThe Ohio State University Department of Emergency Medicine Columbus Ohio USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hyperkalemia is a common electrolyte abnormality identified in the emergency department (ED) and potentially fatal. However, there is no consensus over the potassium threshold that warrants intervention or its treatment algorithm. Commonly used medications are at best temporizing measures, and the roles of binders are unclear in the emergent setting. As the prevalence of comorbid conditions altering potassium homeostasis rises, hyperkalemia becomes more common, and hence there is a need to standardize management. A panel was assembled to synthesize the available evidence and identify gaps in knowledge in hyperkalemia treatment in the ED. The panel was composed of 7 medical practitioners, including 5 physicians, a nurse, and a clinical pharmacist with collective expertise in the areas of emergency medicine, nephrology, and hospital medicine. This panel was sponsored by the American College of Emergency Physicians with a goal to create a consensus document for managing acute hyperkalemia. The panel evaluated the evidence on calcium for myocyte stabilization and potassium shifting and excretion. This article summarizes information on available therapies for hyperkalemia and proposes a hyperkalemia treatment algorithm for the ED practitioner based on the currently available literature and highlights diagnostic pitfalls and evidence gaps.

Indexed as

acute managementalgorithmconsensus recommendationhyperkalemia

Identifiers

PMID34632453
PMCPMC8485984

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.