Evidence map›Paper›PMID 34632382›Full record

ArticleBrain communications2021

Evaluation of [

Toshiki Tezuka, Keisuke Takahata, Morinobu Seki, Hajime Tabuchi, Yuki Momota, Mika Shiraiwa, Natsumi Suzuki, Ayaka Morimoto, Tadaki Nakahara, Yu Iwabuchi and 18 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
6.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 77 citations in OpenAlex.

  1. Dynamic [Molecular neurodegeneration · 2026
    Article
  2. Article
  3. Article
  4. Off-target binding ofAnnals of nuclear medicine · 2026
    Article
  5. Article
  6. Article
  7. Review
  8. Exploring the origins of frequent tau-PET signal in vermal and adjacent regions.European journal of nuclear medicine and molecular imaging · 2025
    Article
  9. Review
  10. Review
  11. Article
  12. Article
  13. Radiosynthesis,ACS chemical neuroscience · 2025
    Article
  14. Neurology. Genetics · 2025
    Article
  15. Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. Temporal progression of tau pathology and neuroinflammation in a rhesus monkey model of Alzheimer's disease.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 4 institutions in 1 country.

Toshiki TezukaDepartment of Neurology, Keio University School of Medicine, Tokyo, Japan.
Keisuke TakahataDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Morinobu SekiDepartment of Neurology, Keio University School of Medicine, Tokyo, Japan.
Hajime TabuchiDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0002-2321-711X
Yuki MomotaDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Mika ShiraiwaDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Natsumi SuzukiDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Ayaka MorimotoDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Tadaki NakaharaDepartment of Diagnostic Radiology, Keio University School of Medicine, Tokyo 160-8582, Japan.
Yu IwabuchiDepartment of Diagnostic Radiology, Keio University School of Medicine, Tokyo 160-8582, Japan.
Eisuke MiuraDepartment of Pathology, Keio University School of Medicine, Tokyo 160-8582, Japan.
Yasuharu YamamotoDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Yasunori SanoDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Kei FunakiDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Bun YamagataDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Ryo UedaOffice of Radiation Technology, Keio University Hospital, Tokyo 160-8582, Japan.ORCID https://orcid.org/0000-0001-8302-155X
Takahito YoshizakiDepartment of Neurology, Keio University School of Medicine, Tokyo, Japan.
Kyoko MashimaDepartment of Neurology, Tokyo Saiseikai Central Hospital, Tokyo 108-0073, Japan.
Mamoru ShibataDepartment of Neurology, Keio University School of Medicine, Tokyo, Japan.
Munenori OyamaDepartment of Neurology, Keio University School of Medicine, Tokyo, Japan.
Kensuke OkadaDepartment of Neurology, Keio University School of Medicine, Tokyo, Japan.
Masahito KubotaDepartment of Neurology, Keio University School of Medicine, Tokyo, Japan.
Hajime OkitaDepartment of Pathology, Keio University School of Medicine, Tokyo 160-8582, Japan.
Masaki TakaoDepartment of Clinical Laboratory, National Center of Neurology and Psychiatry (NCNP), National Center Hospital, Tokyo 187-8551, Japan.
Masahiro JinzakiDepartment of Diagnostic Radiology, Keio University School of Medicine, Tokyo 160-8582, Japan.
Jin NakaharaDepartment of Neurology, Keio University School of Medicine, Tokyo, Japan.
Masaru MimuraDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Daisuke ItoDepartment of Neurology, Keio University School of Medicine, Tokyo, Japan.ORCID https://orcid.org/0000-0002-4740-1675
Keio University · JPInstitute of Brain and Blood Vessels · JPKeio University Hospital · JPSaiseikai Central Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tau aggregates represent a key pathologic feature of Alzheimer's disease and other neurodegenerative diseases. Recently, PET probes have been developed for

Indexed as

Alzheimer’s diseasecorticobasal degenerationprogressive supranuclear palsyTau imagingtauopathy

Identifiers

PMID34632382
PMCPMC8495135
OpenAlexW3194164470

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.