Evidence map›Paper›PMID 34632227›Full record

ArticleACS omega2021

Chemoenzymatic and Protecting-Group-Free Synthesis of 1,4-Substituted 1,2,3-Triazole-α-d-glucosides with Potent Inhibitory Activity toward Lysosomal α-Glucosidase.

Jaggaiah N Gorantla, Santhi Maniganda, Salila Pengthaisong, Lukana Ngiwsara, Phannee Sawangareetrakul, Suwadee Chokchaisiri, Prasat Kittakoop, Jisnuson Svasti, James R Ketudat Cairns

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jaggaiah N GorantlaCenter for Biomolecular Structure, Function and Application, School of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Santhi ManigandaCenter for Biomolecular Structure, Function and Application, School of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Salila PengthaisongCenter for Biomolecular Structure, Function and Application, School of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Lukana NgiwsaraLaboratory of Biochemistry, Chulabhorn Research Institute, Bangkok 10210, Thailand.
Phannee SawangareetrakulLaboratory of Biochemistry, Chulabhorn Research Institute, Bangkok 10210, Thailand.
Suwadee ChokchaisiriCenter for Biomolecular Structure, Function and Application, School of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.
Prasat KittakoopChulabhorn Graduate Institute, Chemical Sciences Program, Chulabhorn Royal Academy, Bangkok 10210, Thailand.ORCID https://orcid.org/0000-0002-5210-3162
Jisnuson SvastiLaboratory of Biochemistry, Chulabhorn Research Institute, Bangkok 10210, Thailand.
James R Ketudat CairnsCenter for Biomolecular Structure, Function and Application, School of Chemistry, Institute of Science, Suranaree University of Technology, Nakhon Ratchasima 30000, Thailand.ORCID https://orcid.org/0000-0003-3042-1626

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

α-Glucosyl triazoles have rarely been tested as α-glucosidase inhibitors, partly due to inefficient synthesis of their precursor α-d-glucosylazide (

Identifiers

PMID34632227
PMCPMC8495876

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.