ArticleACS omega2021
Understanding the Molecular-Level Interactions of Glucosamine-Glycerol Assemblies: A Model System for Chitosan Plasticization.
Article in ACS omega, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
9 citing papers in PubMed, 36 citations in OpenAlex.
- Design and Fabrication of a Chitosan-Based Diaphragm Digital Stethoscope for Heart Sound Acquisition.Micromachines · 2026Article
- Molecular Insights into Miscibility and Mechanical Modulation in PHBV/Chitosan Blends via Atomistic Simulations.Polymer · 2026Article
- Modulating Thermal Stability and Flexibility in Chitosan Films with Neutral Polyol-Boric Acid Complexes.Biomacromolecules · 2025Article
- Fire Resistant Adhesive from Chitosan.Biomacromolecules · 2025Article
- Importance of Primary and Secondary Hydrogen Bonding Interactions of Polyols on the Plasticization of Chitosan.ACS omega · 2024Article
- Article
- Ionic Liquids as Designed, Multi-Functional Plasticizers for Biodegradable Polymeric Materials: A Mini-Review.International journal of molecular sciences · 2024Review
- Chitosan/Virgin-Coconut-Oil-Based System Enriched with Cubosomes: A 3D Drug-Delivery Approach.Marine drugs · 2023Article
- Review
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Glycerol is the most widely used plasticizer for the biopolymer chitosan. However, there remains a lack of understanding of the molecular-level interactions between chitosan and glycerol. Here, we describe an in-depth spectroscopic study of the intermolecular interactions between the monomeric repeating unit of chitosan, glucosamine, and the plasticizer glycerol. Infrared and nuclear magnetic resonance spectroscopy were used to probe glucosamine assembly at high and low concentrations to establish diagnostic signals for intra- and intermolecular glucosamine interactions. Systematic addition of glycerol was found to disrupt intramolecular glucosamine hydrogen bonds and promote glucosamine self-assembly. Furthermore, we observed a significant preference for glycerol binding to the amine functionality of glucosamine. These findings indicate that the plasticization of chitosan with glycerol requires a specific binding motif and likely occurs via the gel theory mechanism.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.