Evidence map›Paper›PMID 34632085›Full record

ArticleWellcome open research2020

Haplotype heterogeneity and low linkage disequilibrium reduce reliable prediction of genotypes for the ‑α

Carolyne M Ndila, Vysaul Nyirongo, Alexander W Macharia, Anna E Jeffreys, Kate Rowlands, Christina Hubbart, George B J Busby, Gavin Band, Rosalind M Harding, Kirk A Rockett and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Wellcome open research, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 3 countries.

Carolyne M NdilaDepartment of Epidemiology and Demography, KEMRI-Wellcome Trust Research Programme, Kilifi, PO BOX 230-80108, Kenya.
Vysaul NyirongoUnited Nation Statistics Division, United Nations, New York, New York, 10017, USA.
Alexander W MachariaDepartment of Epidemiology and Demography, KEMRI-Wellcome Trust Research Programme, Kilifi, PO BOX 230-80108, Kenya.ORCID https://orcid.org/0000-0001-5364-9610
Anna E JeffreysWellcome Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, OX3 7BN, UK.ORCID https://orcid.org/0000-0002-6454-3093
Kate RowlandsWellcome Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, OX3 7BN, UK.
Christina HubbartWellcome Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, OX3 7BN, UK.ORCID https://orcid.org/0000-0001-9576-9581
George B J BusbyWellcome Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, OX3 7BN, UK.
Gavin BandWellcome Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, OX3 7BN, UK.
Rosalind M HardingDepartments of Zoology and Statistics, University of Oxford, Oxford, Oxfordshire, OX1 3SZ, UK.
Kirk A Rockett *Wellcome Centre for Human Genetics, University of Oxford, Oxford, Oxfordshire, OX3 7BN, UK.ORCID https://orcid.org/0000-0002-6369-9299
Thomas N Williams *Department of Epidemiology and Demography, KEMRI-Wellcome Trust Research Programme, Kilifi, PO BOX 230-80108, Kenya.ORCID https://orcid.org/0000-0003-4456-2382
MalariaGEN Consortium
Centre for Human Genetics · GBKenya Medical Research Institute · KEUnited Nations · USUniversity of Oxford · GB

Funding

Medical Research Council G0600230Medical Research Council G0600718Medical Research Council MR/M006212/1Wellcome Trust 077383Wellcome Trust 084538Wellcome Trust 090770Wellcome Trust 092654Wellcome Trust 202800Wellcome Trust 203141Wellcome Trust 204911Wellcome Trust 206194
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Classification and Regression TreeGWAShaplotypesMalariamultinomial regression-modelPredictive Modelsα-thalassaemia

Identifiers

PMID34632085
PMCPMC8474104
OpenAlexW3111220785

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.