Evidence map›Paper›PMID 34632006›Full record

ArticleNeurobiology of stress2021

Analysis of the cerebellar molecular stress response led to first evidence of a role for FKBP51 in brain FKBP52 expression in mice and humans.

Leonie Herrmann, Tim Ebert, Helena Rosen, Bozidar Novak, Alexandra Philipsen, Chadi Touma, Monika Schreckenbach, Nils C Gassen, Theo Rein, Ulrike Schmidt

Open access · goldAbstract read
In one paragraph

Article in Neurobiology of stress, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 2 countries.

Leonie HerrmannGerman Center for Diabetes Research (DZD), Ingolstädter Landstr. 1, 85764, Neuherberg, Germany.
Tim EbertDepartment of Psychiatry and Psychotherapy, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Helena RosenDepartment of Psychiatry and Psychotherapy, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Bozidar NovakMax Planck Institute of Psychiatry, Kraepelinstrasse 2-10, 80804, München, Germany.
Alexandra PhilipsenDepartment of Psychiatry and Psychotherapy, University Hospital Bonn, Venusberg-Campus 1, 53127, Bonn, Germany.
Chadi ToumaDepartment of Behavioural Biology, University of Osnabrück, Barbarastrasse 11, 49076, Osnabrück, Germany.
Monika SchreckenbachMax Planck Institute of Psychiatry, Kraepelinstrasse 2-10, 80804, München, Germany.
Nils C GassenMax Planck Institute of Psychiatry, Kraepelinstrasse 2-10, 80804, München, Germany.
Theo ReinMax Planck Institute of Psychiatry, Kraepelinstrasse 2-10, 80804, München, Germany.
Ulrike SchmidtMax Planck Institute of Psychiatry, Kraepelinstrasse 2-10, 80804, München, Germany.
University Hospital Bonn · DEMax Planck Institute of Psychiatry · DEOsnabrück University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the cerebellar molecular stress response is understudied, we assessed protein expression levels of hypothalamic-pituitary-adrenal (HPA) axis regulators and neurostructural markers in the cerebellum of a male PTSD mouse model and of unstressed vs. stressed male FK506 binding protein 51 (

Indexed as

CerebellumFKBP52FKBP5 knockoutHPA axisPTSD mouse model

Identifiers

PMID34632006
PMCPMC8488056
OpenAlexW3200589304

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.