Observational studyBioMed research international2021
Relationship between CRP Albumin Ratio and the Mortality in Critically Ill Patients with AKI: A Retrospective Observational Study.
Observational study in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Prognostic value of C-reactive protein-to-albumin ratio in acute pancreatitis: a systematic review and meta-analysis.F1000Research · 2023Pooled it
- The C-Reactive Protein/Albumin Ratio Predicts In-Hospital Mortality Across Age Groups.Nutrients · 2026Article
- The role of CAR and SII values in determining mortality in COVID-19 patients: a retrospective observational study.BMC infectious diseases · 2026Observational
- Interpretable machine learning reveals phosphorus-to-albumin ratio as a novel predictor of mortality and acute kidney injury in critically ill pancreatitis patients: a multi-center retrospective analysis.European journal of medical research · 2026Article
- Admission inflammatory and immuno-nutritional indices and in-hospital mortality in emergency department patients admitted to intensive care: a retrospective cohort study.Frontiers in medicine · 2026Article
- Comparative efficacy of fractional CO₂ laser combined with concentrated growth factor (CGF) for treating hypertrophic scars in rabbit ears.Lasers in medical science · 2025Article
- Article
- Efficacy and validation of a clinical model to predict acute kidney injury in severe pneumonia requiring mechanical ventilation in elderly patients: a multicenter retrospective observational analysis.Frontiers in medicine · 2025Article
- The association of serum albumin with 28 day mortality in critically ill patients undergoing dialysis: a secondary analysis based on the eICU collaborative research database.European journal of medical research · 2024Article
- Changes in urinary renal injury markers in children with Mycoplasma pneumoniae pneumonia and a prediction model for related early renal injury.Italian journal of pediatrics · 2024Article
- Association between systemic inflammation biomarkers and mortality in patients with sepsis-associated acute kidney injury receiving intensive care and continuous kidney replacement therapy: results from the RENERGY (REsearches for NEphRology and epidemioloGY) study.Kidney research and clinical practice · 2024Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAKI is known to be associated with inflammation and nutritional status. The novel inflammatory prognostic score CAR (CRP/albumin ratio), which combines inflammation and nutritional status, was hypothesized to be associated with mortality in critically ill AKI patients in this study.
methodsThe included cases were patients admitted to the ICU of Shandong Provincial Hospital from January 2016 to November 2018 and diagnosed with AKI within 48 hours of ICU admission. From the electronic case database of Shandong Provincial Hospital, we extracted the baseline demographic information, vital signs, routine laboratory parameters, complications, and other data. The above records are measured within 48 hours of admission to ICU. The clinical endpoint was the total cause mortality rate in hospital and 2 years. We constructed two multivariate regression models to determine the statistically significant correlation between CAR and mortality and conducted subgroup analysis to determine the mortality among different subgroups.
resultsA total of 580 patients were included in this study. In multivariate regression analysis, higher CAR was associated with an increase in hospital and two-year all-cause mortality in critically ill patients with AKI after adjusting gender, age, respiratory frequency, temperature, and other confounding factors (tertile 3 versus tertile 1: OR, 95% CI: 2.97, 1.70-5.17; 3.03, 1.68-5.47, respectively;
conclusionThe increase of CAR in critically ill patients with AKI was associated with an increased risk of all-cause death.
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