Evidence map›Paper›PMID 34631683›Full record

ReviewFrontiers in bioengineering and biotechnology2021

Systematic Review of the Application of Perinatal Derivatives in Animal Models on Cutaneous Wound Healing.

Melanie Pichlsberger, Urška Dragin Jerman, Hristina Obradović, Larisa Tratnjek, Ana Sofia Macedo, Francisca Mendes, Pedro Fonte, Anja Hoegler, Monika Sundl, Julia Fuchs and 4 more

Open access · goldAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Perinatal derivatives: How to best characterize their multimodal functionsFrontiers in bioengineering and biotechnology · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 5 countries.

Melanie PichlsbergerDivision of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria.
Urška Dragin JermanInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Hristina ObradovićGroup for Hematology and Stem Cells, Institute for Medical Research, University of Belgrade, Belgrade, Serbia.
Larisa TratnjekInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Ana Sofia MacedoLAQV, REQUIMTE, Department of Chemical Sciences-Applied Chemistry Lab, Faculty of Pharmacy, University of Porto, Porto, Portugal.
Francisca MendesiBB-Institute for Bioengineering and Biosciences, Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal.
Pedro FonteiBB-Institute for Bioengineering and Biosciences, Department of Bioengineering, Instituto Superior Técnico, Universidade de Lisboa, Lisboa, Portugal.
Anja HoeglerDivision of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria.
Monika SundlDivision of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria.
Julia FuchsDivision of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria.
Andreina SchoeberleinDepartment of Obstetrics and Feto-maternal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.
Mateja Erdani KreftInstitute of Cell Biology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Slavko MojsilovićGroup for Hematology and Stem Cells, Institute for Medical Research, University of Belgrade, Belgrade, Serbia.
Ingrid Lang-OlipDivision of Cell Biology, Histology and Embryology, Gottfried Schatz Research Center, Medical University of Graz, Graz, Austria.
Medical University of Graz · ATUniversity of Ljubljana · SIUniversity of Belgrade · RSUniversidade do Porto · PTUniversity Hospital of Bern · CHUniversity of Algarve · PTUniversity of Lisbon · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Knowledge of the beneficial effects of perinatal derivatives (PnD) in wound healing goes back to the early 1900s when the human fetal amniotic membrane served as a biological dressing to treat burns and skin ulcerations. Since the twenty-first century, isolated cells from perinatal tissues and their secretomes have gained increasing scientific interest, as they can be obtained non-invasively, have anti-inflammatory, anti-cancer, and anti-fibrotic characteristics, and are immunologically tolerated

Indexed as

animal modelscellscutaneousperinatal derivativesplacentapreclinical studiesskinwound healing

Identifiers

PMID34631683
PMCPMC8498585
OpenAlexW3203919779

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.