Evidence map›Paper›PMID 34631558›Full record

ReviewFrontiers in oncology2021

Recent Advances in Experimental Dendritic Cell Vaccines for Cancer.

Ivan Y Filin, Kristina V Kitaeva, Catrin S Rutland, Albert A Rizvanov, Valeriya V Solovyeva

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
4.3field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it, 74 citations in OpenAlex.

  1. Pooled it
  2. The Landscape of Advanced Therapy Medicinal Products in Slovenian Transfusion Medicine: A Review of Past and Future Outlook.Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie · 2026
    Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Cancer vaccines: current status and future directions.Journal of hematology & oncology · 2025
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. EphA2 in Cancer: Molecular Complexity and Therapeutic Opportunities.International journal of molecular sciences · 2024
    Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Ivan Y FilinInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Kristina V KitaevaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Catrin S RutlandFaculty of Medicine and Health Science, University of Nottingham, Nottingham, United Kingdom.
Albert A RizvanovInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Valeriya V SolovyevaInstitute of Fundamental Medicine and Biology, Kazan Federal University, Kazan, Russia.
Kazan Federal University · RUUniversity of Nottingham · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The development of immunotherapeutic methods for the treatment of oncological diseases have made it possible to improve the effectiveness of standard therapies. There was no breakthrough after first using of personalized therapeutic vaccines based on dendritic cells in clinical practice. A deeper study of the biology of dendritic cells, as well as the use of new approaches and agents for antigenic work, have made it possible to expand the field of application of dendritic cell (DC) vaccines and improve the indicators of cancer patients. In addition, the low toxicity of DC vaccines in clinical trials makes it possible to use promising predictions of their applicability in wider clinical practice. This review examines new approaches and recent advances of the DC vaccine in clinical trials.

Indexed as

antigen-presenting cellsantitumor vaccinescancerdendritic cellsimmunotherapy

Identifiers

PMID34631558
PMCPMC8495208
OpenAlexW3204852225

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.