Evidence map›Paper›PMID 34631543›Full record

ArticleFrontiers in oncology2021

Rectal Cancer Treatment Management: Deep-Learning Neural Network Based on Photoacoustic Microscopy Image Outperforms Histogram-Feature-Based Classification.

Xiandong Leng, Eghbal Amidi, Sitai Kou, Hassam Cheema, Ebunoluwa Otegbeye, William Jr Chapman, Matthew Mutch, Quing Zhu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xiandong LengDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, United States.
Eghbal AmidiDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, United States.
Sitai KouDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, United States.
Hassam CheemaDepartment of Pathology, Washington University in St. Louis, St. Louis, MO, United States.
Ebunoluwa OtegbeyeDivision of Colorectal Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, United States.
William Jr ChapmanDivision of Colorectal Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, United States.
Matthew MutchDivision of Colorectal Surgery, Department of Surgery, Washington University School of Medicine, St. Louis, MO, United States.
Quing ZhuDepartment of Biomedical Engineering, Washington University in St. Louis, St. Louis, MO, United States.
Washington University in St. Louis · US

Funding

Coregistered Photoacoustic and Ultrasound Imaging for Ovarian Cancer Diagnosis and Risk ManagementR01CA237664 · NCI · WASHINGTON UNIVERSITY · PI POWELL, MATTHEW A, SIEGEL, CARY L · 2020 to 2024
$2.6M
Co-registered photoacoustic and ultrasound imaging for non-invasive ovarian canR01CA151570 · NCI · WASHINGTON UNIVERSITY · PI BREWER, MOLLY A., ZHU, QUING · 2011 to 2015
$1.6M
NCI NIH HHS R01 CA151570NCI NIH HHS R01 CA237664
6 · The paper itself

Abstract

We have developed a novel photoacoustic microscopy/ultrasound (PAM/US) endoscope to image post-treatment rectal cancer for surgical management of residual tumor after radiation and chemotherapy. Paired with a deep-learning convolutional neural network (CNN), the PAM images accurately differentiated pathological complete responders (pCR) from incomplete responders. However, the role of CNNs compared with traditional histogram-feature based classifiers needs further exploration. In this work, we compare the performance of the CNN models to generalized linear models (GLM) across 24

Indexed as

machine learningphotoacoustic imaging of rectal cancerrectal cancerregression analysisultrasound imaging

Identifiers

PMID34631543
PMCPMC8495416
OpenAlexW3203857753

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.