Evidence map›Paper›PMID 34631538›Full record

ArticleFrontiers in oncology2021

Actin Beta-Like 2 as a New Mediator of Proliferation and Migration in Epithelial Ovarian Cancer.

Nicole Elisabeth Topalov, Doris Mayr, Clemens Scherer, Anca Chelariu-Raicu, Susanne Beyer, Anna Hester, Fabian Kraus, Mingjun Zheng, Till Kaltofen, Thomas Kolben and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 4 institutions in 1 country.

Nicole Elisabeth TopalovDepartment of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Doris MayrInstitute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.
Clemens SchererDepartment of Medicine I, University Hospital, LMU Munich, Munich, Germany.
Anca Chelariu-RaicuDepartment of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Susanne BeyerDepartment of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Anna HesterDepartment of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Fabian KrausDepartment of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Mingjun ZhengDepartment of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Till KaltofenDepartment of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Thomas KolbenDepartment of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Alexander BurgesDepartment of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Sven MahnerDepartment of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Fabian TrillschDepartment of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Udo JeschkeDepartment of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Bastian CzogallaDepartment of Obstetrics and Gynecology, University Hospital, LMU Munich, Munich, Germany.
Ludwig-Maximilians-Universität München · DELMU Klinikum · DEGerman Centre for Cardiovascular Research · DEUniversity Hospital Augsburg · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The impact of Actin beta-like 2 (ACTBL2), a novel described actin isoform, on epithelial ovarian cancer (EOC) biology has not been investigated so far. In this study, we analyzed the prognostic and functional significance of ACTBL2 and its regulatory element Nuclear factor of activated T-cells 5 (NFAT5). The expression of ACTBL2 and NFAT5 was examined in tissue microarrays of 156 ovarian cancer patients by immunohistochemistry. Aiming to assess the molecular impact of ACTBL2 on cellular characteristics, functional assays were executed

Indexed as

actin beta-like 2epithelial ovarian cancermigrationnuclear factor of activated T-cells 5prognosisproliferation

Identifiers

PMID34631538
PMCPMC8495414
OpenAlexW3202605561

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.