ArticleFrontiers in oncology2021
A Clinical-Radiomics Nomogram for Preoperative Prediction of Lymph Node Metastasis in Gallbladder Cancer.
Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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13 citing papers in PubMed, 19 citations in OpenAlex.
- Genetic characteristics and clinical-specific survival prediction in elderly patients with gallbladder cancer: a genetic and population-based study.Frontiers in endocrinology · 2023Trial
- Prediction of tumor regression grading in rectal cancer neoadjuvant chemoradiotherapy: a habitat radiomics analysis of imaging biomarker.BMC medical imaging · 2026Article
- Deep learning-based segmentation of gallbladder cancer on abdominal computed tomography scans: a multicenter study.Abdominal radiology (New York) · 2025Article
- An MRI-based model for preoperative prediction of tertiary lymphoid structures in patients with gallbladder cancer.Insights into imaging · 2025Article
- Update on the Role of Imaging in the Diagnosis, Staging, and Prognostication of Gallbladder Cancer.The Indian journal of radiology & imaging · 2025Review
- Pre-operative T-stage discrimination in gallbladder cancer using machine learning and DeepSeek-R1.Frontiers in oncology · 2025Article
- Preoperative prediction of lymph node metastasis in patients with ovarian cancer using contrast-enhanced computed tomography-based intratumoral and peritumoral radiomics features.Frontiers in oncology · 2025Article
- Radiomic nomograms in CT diagnosis of gall bladder carcinoma: a narrative review.Discover oncology · 2024Review
- Applications of artificial intelligence in biliary tract cancers.Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2024Review
- Gross tumour volume radiomics for prognostication of recurrence & death following radical radiotherapy for NSCLC.NPJ precision oncology · 2022Article
- Preoperative Prediction of Lymph Node Metastasis of Pancreatic Ductal Adenocarcinoma Based on a Radiomics Nomogram of Dual-Parametric MRI Imaging.Frontiers in oncology · 2022Article
- A meta-analysis of based radiomics for predicting lymph node metastasis in patients with biliary tract cancers.Frontiers in surgery · 2022Review
- Progress in gallbladder cancer with lymph node metastasis.Frontiers in oncology · 2022Review
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe aim of the current study was to develop and validate a nomogram based on CT radiomics features and clinical variables for predicting lymph node metastasis (LNM) in gallbladder cancer (GBC).
methodsA total of 353 GBC patients from two hospitals were enrolled in this study. A Radscore was developed using least absolute shrinkage and selection operator (LASSO) logistic model based on the radiomics features extracted from the portal venous-phase computed tomography (CT). Four prediction models were constructed based on the training cohort and were validated using internal and external validation cohorts. The most effective model was then selected to build a nomogram.
resultsThe clinical-radiomics nomogram, which comprised Radscore and three clinical variables, showed the best diagnostic efficiency in the training cohort (AUC = 0.851), internal validation cohort (AUC = 0.819), and external validation cohort (AUC = 0.824). Calibration curves showed good discrimination ability of the nomogram using the validation cohorts. Decision curve analysis (DCA) showed that the nomogram had a high clinical utility.
conclusionThe findings showed that the clinical-radiomics nomogram based on radiomics features and clinical parameters is a promising tool for preoperative prediction of LN status in patients with GBC.
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