Evidence map›Paper›PMID 34631504›Full record

ArticleToxicological research2021

Flavonoid fractions of diosmin and hesperidin mitigate lead acetate-induced biochemical, oxidative stress, and histopathological alterations in Wistar rats.

Ibrahim Yusuf Lamidi, Hudu Garba Mikail, Sani Adamu, Isaac Oluwatobi Akefe, Mohammed Bashir Tijjani, Sabo Isa Salihu, Aisha Omobolanle Olatunji, Abdussalam Hassan, Nubwa Daniel, Victoria Aderonke Adegoke

RetractedOpen access · greenAbstract readRetracted Publication
In one paragraph

Article in Toxicological research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.3field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
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  4. Lipids and Secretory Vesicle Exocytosis.Advances in neurobiology · 2023
    Article
  5. In vitro anthelmintic activity ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2022
    Article
  6. Article
  7. Pharmacology of Diosmin, a Citrus Flavone Glycoside: An Updated Review.European journal of drug metabolism and pharmacokinetics · 2022
    Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 1 country.

Ibrahim Yusuf LamidiDepartment of Veterinary Pharmacology and Toxicology, University of Maiduguri, Maiduguri, Nigeria.
Hudu Garba MikailDepartment of Veterinary Pharmacology and Toxicology, University of Abuja, Abuja, Nigeria.
Sani AdamuDepartment of Veterinary Pathology, Ahmadu Bello University Zaria, Zaria, Nigeria.
Isaac Oluwatobi AkefeDepartment of Physiology, Biochemistry, and Pharmacology, Faculty of Veterinary Medicine, University of Jos, Jos, Nigeria.ORCID 0000-0003-4738-0701
Mohammed Bashir TijjaniDepartment of Veterinary Pharmacology and Toxicology, University of Maiduguri, Maiduguri, Nigeria.
Sabo Isa SalihuDepartment of Veterinary Pharmacology and Toxicology, University of Maiduguri, Maiduguri, Nigeria.
Aisha Omobolanle OlatunjiDepartment of Veterinary Pharmacology and Toxicology, University of Ilorin, Ilorin, Nigeria.
Abdussalam HassanDepartment of Veterinary Pathology, University of Maiduguri, Maiduguri, Nigeria.
Nubwa DanielDepartment of Veterinary Pharmacology and Toxicology, University of Maiduguri, Maiduguri, Nigeria.
Victoria Aderonke AdegokeDepartment of Science and Laboratory Technology, Ekiti State University, Ado Ekiti, Nigeria.
University of Maiduguri · NGAhmadu Bello University · NGEkiti State University · NGUniversity of Abuja · NGUniversity of Ilorin · NGUniversity of Jos · NG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aims at investigating the protective effects of flavonoid fractions of diosmin and hesperidin in mitigating sub-chronic lead acetate-induced biochemical, oxidative stress, and histopathological alterations in adult male Wistar rats. Forty animals were randomly assigned into five groups, each consisting of eight animals. Group I animals was treated with deionised water only, group II, IV, and V were administered lead acetate 90 mg/Kg body weight (1/20th of the LD

Indexed as

BiochemicalDiosminFlavonoidsHesperidinOxidative stressZinc protoporphyrin

Identifiers

PMID34631504
PMCPMC8476667
OpenAlexW3157142470

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.