Evidence map›Paper›PMID 34631265›Full record

ArticleDermatology practical & conceptual2021

Potential Utility of Oral Mucosal Capillaroscopy as an Indicator of Microvascular Damage in Behçet Disease: A Preliminary Study.

Abdullah Demirbaş, Ömer Faruk Elmas, Gözde Ulutaş Demirbaş, Mustafa Atasoy, Ümit Türsen, Torello Lotti

Open access · diamondAbstract read
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Article in Dermatology practical & conceptual, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 6 institutions in 3 countries.

Abdullah DemirbaşDepartment of Dermatology, Kütahya Health Sciences University.
Ömer Faruk ElmasDepartment of Dermatology, Kırıkkale University Kırıkkale, Turkey.
Gözde Ulutaş DemirbaşDepartment of Dermatology, Evliya Çelebi Training and Research Hospital, Kütahya, Turkey.
Mustafa AtasoyHealth Science University, Kayseri City Hospital, Department of Dermatology, Kayseri, Turkey.
Ümit TürsenMersin University, Department of Dermatology, Mersin, Turkey.
Torello LottiDepartment of Dermatology, Guglielmo Marconi University, Rome, Italy.
Dumlupinar University · TRIzmir Kâtip Çelebi University · TRKayseri Eğitim ve Araştırma Hastanesi · TRMarconi University · ITMersin Üniversitesi · TRUniversity Dermatology · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionBehçet disease (BD) is an auto-inflammatory condition characterized by multisystemic vasculitis. Oral mucosal capillaroscopy is an easy-to-use, repeatable, non-invasive method for evaluating mucosal microvasculature, contributing to the differential diagnosis and prognosis of various acute and chronic inflammatory diseases.

objectivesThis study aims to characterize and describe the oral labial mucosal capillary findings in patients with BD using handheld dermatoscopy and to investigate the relationship between the capillary findings and the severity of the disease.

methodsThis cross-sectional study included patients with BD and healthy subjects. Capillaroscopic examination of the oral labial mucosa in each subject was performed by a handheld dermatoscope using polarized light. The clinical severity of BD was evaluated using Krause's Clinical Severity Scoring for BD.

resultsSixty patients with BD and 60 healthy subjects were enrolled in the study. The frequencies of irregular capillaries, microhemorrhages, glomerular vessels, megacapillaries, and tortuous vessels were statistically significantly higher in the patient group when compared to the healthy individuals. In addition, a correlation was detected between the oral mucosal capillaroscopic findings and disease duration, severity, and vascular complications.

conclusionsOur study is the first to explore the potential role of oral mucosal capillaroscopic examination in patients with BD. Data obtained from this study indicated that oral mucosal capillaroscopy may be a useful tool to demonstrate microvascular damage in patients with BD.

Indexed as

Behçet diseasecapillaryhandheld dermoscopymicrovascular damagemucoscopyoral labial mucosa

Identifiers

PMID34631265
PMCPMC8480447
OpenAlexW3201796936

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.