Evidence map›Paper›PMID 34631174›Full record

ArticleCase reports in critical care2021

New-Onset Systemic Capillary Leak Syndrome in an Adult Patient with COVID-19.

Daniel B Knox, Vivian Lee, Lindsay Leither, Samuel M Brown

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in critical care, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Systemic capillary leak syndrome.Nature reviews. Disease primers · 2024
    Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Limb Fasciotomy for COVID-19 Patients: Is the Chance to Cut a Chance to Cure?Plastic and reconstructive surgery. Global open · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Daniel B KnoxPulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, UT, USA.ORCID https://orcid.org/0000-0002-8991-1235
Vivian LeePulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, UT, USA.
Lindsay LeitherPulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, UT, USA.
Samuel M BrownPulmonary and Critical Care Medicine, Intermountain Medical Center, Murray, UT, USA.ORCID https://orcid.org/0000-0003-1206-6261
University of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systemic capillary leak syndrome (SCLS) is a rare disorder manifesting as shock, hemoconcentration, and hypoalbuminemia, which may be either idiopathic or secondary to an underlying disease process. We report a case of an adult with COVID-19 infection associated with new onset SCLS. Our case joins only two other cases of new SCLS associated with COVID-19 infection reported in the literature. The clinical and laboratory findings in this case are distinct from findings seen in COVID-19 cytokine storm syndrome. Whether our therapeutic approach was efficacious is unknown. Further research into causes and therapies for these syndromes is urgently indicated.

Identifiers

PMID34631174
PMCPMC8497160
OpenAlexW3204485343

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.