Evidence map›Paper›PMID 34631102›Full record

ArticleRespirology case reports2021

A case of prominent immunoglobulin G4-positive lymphadenopathy in response to microscopic lung cancer.

Motoi Yuzawa, Hiromitsu Ohta, Motoko Nomura, Kentaro Minegishi, Hisashi Oshiro, Yasuhiro Yamaguchi

Open access · goldAbstract readCase Reports
In one paragraph

Article in Respirology case reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Motoi YuzawaDepartment of Respiratory Medicine, Saitama Medical Center Jichi Medical University Saitama Japan.
Hiromitsu OhtaDepartment of Respiratory Medicine, Saitama Medical Center Jichi Medical University Saitama Japan.ORCID https://orcid.org/0000-0001-9893-0254
Motoko NomuraDepartment of Respiratory Medicine, Saitama Medical Center Jichi Medical University Saitama Japan.
Kentaro MinegishiDepartment of Thoracic Surgery, Saitama Medical Center Jichi Medical University Saitama Japan.
Hisashi OshiroDepartment of Pathology, Saitama Medical Center Jichi Medical University Saitama Japan.
Yasuhiro YamaguchiDepartment of Respiratory Medicine, Saitama Medical Center Jichi Medical University Saitama Japan.
Jichi Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunoglobulin G4 (IgG4)-related disease is established as a new clinical entity, characterized by high levels of plasma IgG4 and IgG4-positive plasma cell infiltration. However, the elevation of plasma IgG4 and infiltration of IgG4-positive cells have been observed in other diseases, including malignancy. We experienced a case of prominent IgG4-positive lymphadenopathy, which was diagnosed as a reactive lesion in response to lung cancer. The cancerous lesion was so small in size that it was difficult to reveal the coexisting lung cancer. Surgical lymph node biopsy and endobronchial ultrasound-guided transbronchial needle aspiration did not reveal lymph node metastasis of cancer. Mediastinal lymph node dissection finally revealed it. After the right upper lobectomy, the patient underwent postoperative chemotherapy and remains cancer-free after 1 year. Our case suggests that close examination and careful follow-up are necessary when IgG4-positive lymphadenopathy is observed.

Indexed as

EBUS‐TBNAimmunoglobulin G4‐related diseaselung cancerlymphadenopathythoracoscopic lymph node biopsy

Identifiers

PMID34631102
PMCPMC8488362
OpenAlexW3204805886

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.