Evidence map›Paper›PMID 34631039›Full record

ArticleRSC advances2020

Rigor and reproducibility in polymer nanoparticle synthesis and characterization.

Kenneth R Sims, Julian P Maceren, Alexander Ian Strand, Brian He, Clyde Overby, Danielle S W Benoit

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in RSC advances, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kenneth R SimsDept. of Biomedical Engineering, University of Rochester, Rochester, NY, USA.
Julian P MacerenDept. of Chemistry, University of Rochester, Rochester, NY, USA.
Alexander Ian StrandDept. of Biomedical Engineering, University of Rochester, Rochester, NY, USA.
Brian HeDept. of Statistics, University of Rochester, Rochester, NY, USA.
Clyde OverbyDept. of Biomedical Engineering, University of Rochester, Rochester, NY, USA.ORCID 0000-0001-7033-280X
Danielle S W BenoitDept. of Biomedical Engineering, University of Rochester, Rochester, NY, USA.ORCID 0000-0001-7137-8164

Funding

Evaluation of a Novel Anti-Caries Approach to Modulate Virulence of S. mutansR01DE018023 · NIDCR · UNIVERSITY OF ROCHESTER · PI KOO, HYUN · 2008 to 2019
$3.4M
NIH Training Grant in Chemistry-Biology InterfaceT32GM145461 · NIGMS · UNIVERSITY OF ROCHESTER · PI KARA L. BREN, Bradley L. Nilsson · 2022 to 2026
$988k
NIH Training Grant in the Chemistry-Biology InterfaceT32GM118283 · NIGMS · UNIVERSITY OF ROCHESTER · PI BREN, KARA L., FASAN, RUDI · 2017 to 2021
$850k
Engineered pH-Responsive Nanoparticle Drug Delivery to Inhibit Oral Biofilm FormationF31DE026944 · NIDCR · UNIVERSITY OF ROCHESTER · PI SIMS, KENNETH R · 2017 to 2019
$124k
NIDCR NIH HHS F31 DE026944NIDCR NIH HHS R01 DE018023NIGMS NIH HHS T32 GM118283NIGMS NIH HHS T32 GM145461
6 · The paper itself

Abstract

Standardized process improvement methods and tools were used to enhance the rigor and reproducibility of diblock copolymer nanoparticle (NP) synthesis and characterization. Models linking design parameters with NP characteristics boosted process control for NP synthesis, which may improve translation and commercialization of NP research.

Identifiers

PMID34631039
PMCPMC8496373

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.