Evidence map›Paper›PMID 34630956›Full record

ArticleIranian journal of basic medical sciences2021

Efficacy of true cinnamon (

Gayan Kanchana Wijesinghe, Thaís Rossini de Oliveira, Flávia Camila Maia, Simone Busato de Feiria, Janaina Priscila Barbosa, Felipe Joia, Giovana Cláudia Boni, José Francisco Höfling

Open access · greenAbstract read
In one paragraph

Article in Iranian journal of basic medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 21 citations in OpenAlex.

  1. Frontiers in pharmacology · 2026
    Article
  2. Review
  3. Review
  4. Exploring the Antibiofilm Effect of Sertraline in Synergy withPharmaceuticals (Basel, Switzerland) · 2024
    Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Synergistic Antibiofilm Action ofMolecules (Basel, Switzerland) · 2023
    Article
  10. Article
  11. Article
  12. Frontiers in cellular and infection microbiology · 2022
    Review
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Gayan Kanchana WijesingheArea of Microbiology and Immunology, Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, SP, Brazil.
Thaís Rossini de OliveiraArea of Microbiology and Immunology, Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, SP, Brazil.
Flávia Camila MaiaArea of Microbiology and Immunology, Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, SP, Brazil.
Simone Busato de FeiriaArea of Microbiology and Immunology, Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, SP, Brazil.
Janaina Priscila BarbosaArea of Microbiology and Immunology, Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, SP, Brazil.
Felipe JoiaArea of Microbiology and Immunology, Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, SP, Brazil.
Giovana Cláudia BoniArea of Microbiology and Immunology, Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, SP, Brazil.
José Francisco HöflingArea of Microbiology and Immunology, Department of Oral Diagnosis, Piracicaba Dental School, State University of Campinas, SP, Brazil.
Universidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe essential oil (EO) extracted from MATERIALS AND

methodsThe effect of EO vapor was evaluated using a microatmosphere technique. CLSI microdilution assay was employed in determining the Minimum Inhibitory (MIC) and Fungicidal Concentrations (MFC). Killing time was determined using a standard protocol. The effect of EO on established biofilms was quantified and visualized using XTT and Scanning Electron Microscopy (SEM), respectively. Post-exposure intracellular changes were visualized using Transmission Electron Microscopy (TEM). The toxicological assessment was carried out with the Human Keratinocyte cell line. The chemical composition of EO was evaluated using Gas Chromatography-Mass Spectrometry (GC-MS).

resultsAll test strains were susceptible to cinnamon oil vapor. EO exhibited MIC value 1.0 mg/ml and MFC value 2.0 mg/ml against test strains. The killing time of cinnamon oil was 6 hr. Minimum Biofilm Inhibitory Concentration (MBIC

conclusionC.

Indexed as

Antifungal agentBiofilmsCandida spp.Cinnamomum verumEssential oil

Identifiers

PMID34630956
PMCPMC8487610
OpenAlexW3173466090

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.