ArticleWorld journal of hepatology2021
Global prevalence of hepatitis B virus serological markers among healthcare workers: A systematic review and meta-analysis.
Article in World journal of hepatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 3 of them syntheses that pooled it.
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Who cites it
27 citing papers in PubMed, 3 syntheses or guidelines pooled it, 46 citations in OpenAlex.
- Factors associated with accidental exposure to infectious agent among health care providers in Ethiopia: a systematic review and meta-analysis of data published from 2014 to 2023.Archives of public health = Archives belges de sante publique · 2025Pooled it
- Prevalence of hepatitis B virus infection and its associated factors in Ethiopia: a recent systematic review and meta-analysis.BMC infectious diseases · 2025Pooled it
- Seroprevalence of Hepatitis B Among Healthcare Workers in Asia and Africa and Its Association With Their Knowledge and Awareness: A Systematic Review and Meta-Analysis.Frontiers in public health · 2022Pooled it
- Prevalence and control strategies of blood-borne occupational exposures among healthcare workers in Shaoxing Second Hospital from 2020 to 2025.The Journal of international medical research · 2026Article
- Assessment of hepatitis B and tetanus toxoid vaccination coverage and associated factors among healthcare workers at Kabul University of Medical Sciences affiliated hospitals in Afghanistan.BMC public health · 2026Article
- Prevalence and risk factors for hepatitis B virus infection among expectant mothers in Jirapa Municipality, Upper West Region, Ghana: a facility-based cross-sectional study.BMC public health · 2026Article
- Non-hospital occupational blood exposure accidents: A nine-year retrospective analysis of post-exposure HIV, hepatitis B and C risk management in the Netherlands.Epidemiology and infection · 2026Article
- Knowledge, Attitudes, Practices, and Associated Factors of Healthcare Workers Toward Hepatitis B Post-Exposure Prophylaxis in Ethiopia: A Cross-Sectional Study.Health science reports · 2026Article
- B-cell DNA methylation signature in response to hepatitis B virus vaccination in females and males.Frontiers in immunology · 2026Article
- Hepatitis B virus infection: seroprevalence, knowledge, attitude and practice among healthcare workers at Abu-Salim trauma hospital, Tripoli-Libya.The Pan African medical journal · 2026Article
- Seroprevalence of markers and immunization for hepatitis B in community health workers: a scoping review.Revista da Escola de Enfermagem da U S P · 2026Article
- Evaluation of hepatitis B vaccine effectiveness among fully vaccinated healthcare workers in Ethiopia.BMC infectious diseases · 2025Article
- Immunological characterization of hepatitis B core antigen antibody among vaccinated adults lacking hepatitis B surface antigen in ethiopia: A multicenter facility-based study.Scientific reports · 2025Article
- Sero-prevalence of hepatitis B among health facility staff in Salima district, Malawi - a cross-sectional study.BMC infectious diseases · 2025Article
- Hepatitis B vaccination status, knowledge and associated factors among healthcare professionals in Dongola, Sudan, 2024: a cross-sectional study.BMC infectious diseases · 2025Article
- Assessing the psychometric properties of a modified vaccine hesitancy scale for measuring hepatitis B vaccine hesitancy among healthcare workers in Southern Ghana.BMC public health · 2025Article
- Article
- Self-reported exposure to blood and body fluids and serological evidence of lifetime exposure to hepatitis B virus among health care workers in Ghana: a cross-sectional study.BMC infectious diseases · 2024Article
- Article
- Occupational exposure to Hepatitis B virus, disease burden and pathways for postexposure prophylaxis management: recommendations for healthcare workers in highly endemic settings.Infection prevention in practice · 2024Review
Corrections and comments
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Authors and funding
31 authors at 7 institutions in 1 country.
Funding
Abstract
backgroundThe hepatitis B virus (HBV) infection is a global public health concern that affects about 2 billion people and causes 1 million people deaths yearly. HBV is a blood-borne disease and healthcare workers (HCWs) are a high-risk group because of occupational hazard to patients' blood. Different regions of the world show a highly variable proportion of HCWs infected and/or immunized against HBV. Global data on serologic markers of HBV infection and immunization in HCWs are very important to improve strategies for HBV control.
aimTo determine the worldwide prevalence of HBV serological markers among HCWs.
methodsIn this systematic review and meta-analyses, we searched PubMed and Excerpta Medica Database (Embase) to identify studies published between 1970 and 2019 on the prevalence of HBV serological markers in HCWs worldwide. We also manually searched for references of relevant articles. Four independent investigators selected studies and included those on the prevalence of each of the HBV serological markers including hepatitis B surface antigen (HBsAg), hepatitis e antigen (HBeAg), immunoglobulin M anti-HBc, and anti-HBs. Methodological quality of eligible studies was assessed and random-effect model meta-analysis resulted in the pooled prevalence of HBV serological markers HBV infection in HCWs. Heterogeneity (
resultsWe reviewed 14059 references, out of which 227 studies corresponding to 448 prevalence data among HCWs (224936 HCWs recruited from 1964 to 2019 in 71 countries) were included in this meta-analysis. The pooled seroprevalences of current HBsAg, current HBeAg, and acute HBV infection among HCWs were 2.3% [95% confidence interval (CI): 1.9-2.7], 0.2% (95%CI: 0.0-1.7), and 5.3% (95%CI: 1.4-11.2), respectively. The pooled seroprevalences of total immunity against HBV and immunity acquired by natural HBV infection in HCWs were 56.6% (95%CI: 48.7-63.4) and 9.2% (95%CI: 6.8-11.8), respectively. HBV infection was more prevalent in HCWs in low-income countries, particularly in Africa. The highest immunization rates against HBV in HCWs were recorded in urban areas and in high-income countries including Europe, the Eastern Mediterranean and the Western Pacific.
conclusionNew strategies are needed to improve awareness, training, screening, vaccination, post-exposure management and treatment of HBV infection in HCWs, and particularly in low-income regions.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.