ArticleComputer methods in applied mechanics and engineering2021
A computationally efficient physiologically comprehensive 3D-0D closed-loop model of the heart and circulation.
Article in Computer methods in applied mechanics and engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.
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Who cites it
28 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Simulating impaired left ventricular-arterial coupling in aging and disease: a systematic review.Biomedical engineering online · 2024Pooled it
- Elucidating the cellular determinants of the end-systolic pressure-volume relationship of the heart via computational modelling.The Journal of physiology · 2026Article
- A Poroelastic Computational Modeling Framework Coupling Left Ventricular Cardiac Mechanics and Myocardial Perfusion.International journal for numerical methods in biomedical engineering · 2026Article
- A finite element computational framework coupling four-chamber heart mechanics with the systemic and pulmonary circulations.Research square · 2026Article
- Coupling Models of Resistive Valves to Muscle Mechanics in Cardiac Fluid-Structure Interaction Simulations.International journal for numerical methods in biomedical engineering · 2025Article
- Systematic computational assessment of atrial function impairment due to fibrotic remodeling in electromechanical properties.PLoS computational biology · 2025Article
- Article
- Advection versus diffusion in brain ventricular transport.Fluids and barriers of the CNS · 2025Article
- Rhythm control benefits left ventricular function compared with rate control in patients with atrial fibrillation: A computational study.Heart rhythm O2 · 2025Article
- Computational modelling for improved translation of cardiac inotropic and lusitropic drug effects from rats to humans.Journal of pharmacological and toxicological methods · 2025Article
- A universal material model subroutine for soft matter systems.Engineering with computers · 2025Article
- Biomechanics of soft biological tissues and organs, mechanobiology, homeostasis and modelling.Journal of the Royal Society, Interface · 2025Review
- Personalized computational electro-mechanics simulations to optimize cardiac resynchronization therapy.Biomechanics and modeling in mechanobiology · 2024Article
- Simulating cardiac fluid dynamics in the human heart.PNAS nexus · 2024Article
- Whole-heart electromechanical simulations using Latent Neural Ordinary Differential Equations.NPJ digital medicine · 2024Article
- Mathematical analysis of left ventricular elastance with respect to afterload change during ejection phase.PLoS computational biology · 2024Article
- A Modular Framework for Implicit 3D-0D Coupling in Cardiac Mechanics.Computer methods in applied mechanics and engineering · 2024Article
- Approaches to vascular network, blood flow, and metabolite distribution modeling in brain tissue.Biophysical reviews · 2023Review
- Cell to whole organ global sensitivity analysis on a four-chamber heart electromechanics model using Gaussian processes emulators.PLoS computational biology · 2023Article
- GPU accelerated digital twins of the human heart open new routes for cardiovascular research.Scientific reports · 2023Article
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Authors and funding
8 authors.
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Abstract
Computer models of cardiac electro-mechanics (EM) show promise as an effective means for the quantitative analysis of clinical data and, potentially, for predicting therapeutic responses. To realize such advanced applications methodological key challenges must be addressed. Enhanced computational efficiency and robustness is crucial to facilitate, within tractable time frames, model personalization, the simulation of prolonged observation periods under a broad range of conditions, and physiological completeness encompassing therapy-relevant mechanisms is needed to endow models with predictive capabilities beyond the mere replication of observations. Here, we introduce a universal feature-complete cardiac EM modeling framework that builds on a flexible method for coupling a 3D model of bi-ventricular EM to the physiologically comprehensive 0D
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.