Evidence map›Paper›PMID 34630607›Full record

ArticleEvidence-based complementary and alternative medicine : eCAM2021

Effects of ShenLing BaiZhu San Supplementation on Gut Microbiota and Oxidative Stress in Rats with Ulcerative Colitis.

Daxing Gu, Shanshan Zhou, Lili Yao, Ying Tan, Xingzi Chi, Dayou Shi, Shining Guo, Cui Liu

Abstract read
In one paragraph

Article in Evidence-based complementary and alternative medicine : eCAM, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Protective effect of Zhizi Huangqi Shanzha formula on aflatoxin poisoning in mice and its effect on intestinal flora.Journal of traditional Chinese medicine = Chung i tsa chih ying wen pan · 2024
    Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Traditional Chinese Medicine Alleviates Ulcerative Colitis via Modulating Gut Microbiota.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Daxing GuCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Shanshan ZhouCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Lili YaoCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Ying TanCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Xingzi ChiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Dayou ShiCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Shining GuoCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.
Cui LiuCollege of Veterinary Medicine, South China Agricultural University, Guangzhou 510642, China.ORCID https://orcid.org/0000-0002-0609-0073

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to evaluate the effect of gut microbiota and antioxidation of Shenling Baizhu San (SLBZS) as a supplement in a rat model of ulcerative colitis (UC) induced by 2,4,6-trinitrobenzenesulfonic acid (TNBS). Acute intestinal inflammation was induced in 40 male SD rats aged 4 weeks with 100 mg/kg TNBS, and then three dosages of SLBZS (0.5 g/kg, 1 g/kg, and 1.5 g/kg) were administered for eight days, respectively. Faecal microbiome composition was assessed by 16S rRNA high-throughput sequencing. The result indicated that SLBZS could reduce the diversity of gut microbiota and increased its abundance. At the genus level, the relative abundance of SCFAs producing bacteria including

Identifiers

PMID34630607
PMCPMC8500740

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.