Evidence map›Paper›PMID 34630428›Full record

ArticleFrontiers in immunology2021

Venetoclax or Ruxolitinib in Pre-Transplant Conditioning Lowers the Engraftment Barrier by Different Mechanisms in Allogeneic Stem Cell Transplant Recipients.

Joanne E Davis, Kelei Du, Mandy J Ludford-Menting, Ashvind Prabahran, Eric Wong, Nicholas D Huntington, Rachel M Koldej, David S Ritchie

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Synergistic venetoclax and anti-CD3 therapy for control of alloreactive response in hematopoietic stem cell transplantation.American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Joanne E DavisAustralian Cancer Research Foundation (ACRF) Translational Research Laboratory, The Royal Melbourne Hospital, Melbourne, VIC, Australia.
Kelei DuAustralian Cancer Research Foundation (ACRF) Translational Research Laboratory, The Royal Melbourne Hospital, Melbourne, VIC, Australia.
Mandy J Ludford-MentingAustralian Cancer Research Foundation (ACRF) Translational Research Laboratory, The Royal Melbourne Hospital, Melbourne, VIC, Australia.
Ashvind PrabahranAustralian Cancer Research Foundation (ACRF) Translational Research Laboratory, The Royal Melbourne Hospital, Melbourne, VIC, Australia.
Eric WongAustralian Cancer Research Foundation (ACRF) Translational Research Laboratory, The Royal Melbourne Hospital, Melbourne, VIC, Australia.
Nicholas D HuntingtonMolecular Immunology Division, The Walter and Eliza Hall Institute of Medical Research, Melbourne, VIC, Australia.
Rachel M KoldejAustralian Cancer Research Foundation (ACRF) Translational Research Laboratory, The Royal Melbourne Hospital, Melbourne, VIC, Australia.
David S RitchieAustralian Cancer Research Foundation (ACRF) Translational Research Laboratory, The Royal Melbourne Hospital, Melbourne, VIC, Australia.
Australian Cancer Research Foundation · AUThe Royal Melbourne Hospital · AUUniversity of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Allogeneic stem cell transplantation (alloSCT) is utilised to cure haematological malignancies through a combination of conditioning regimen intensity and immunological disease control

Indexed as

Hematopoietic Stem Cell TransplantationTransplantation ConditioningAnimalsBridged Bicyclo Compounds, HeterocyclicFemaleGenes, MHC Class IIInterferonsJanus Kinase InhibitorsMaleMiceMice, Inbred BALB CMice, Inbred C57BLMice, KnockoutNitrilesProto-Oncogene Proteins c-bcl-2PyrazolesBcl2 protein, mouseBridged Bicyclo Compounds, HeterocyclicInterferonsJanus Kinase InhibitorsNitrilesProto-Oncogene Proteins c-bcl-2PyrazolesPyrimidinesruxolitinibSulfonamidesvenetoclaxallogeneic stem cell transplantationgraft versus host diseasegraft versus tumour effectMHC class-IIreduced intensity conditioningruxolitinibvenetoclax

Identifiers

PMID34630428
PMCPMC8498041
OpenAlexW3203720228

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.