Evidence map›Paper›PMID 34630292›Full record

ArticleFrontiers in neurology2021

Efficacy and Safety of Adherence to dl-3-n-Butylphthalide Treatment in Patients With Non-disabling Minor Stroke and TIA-Analysis From a Nationwide, Multicenter Registry.

Zefeng Tan, Yin Zhao, Wanyong Yang, Shenwen He, Yan Ding, Anding Xu

Erratum issued Registry-linked trialAbstract read
In one paragraph

Article in Frontiers in neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT07230587 (A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Long-Term Efficacy of Butylphthalide in Patients With Minor Acute Ischemic Stroke), which is not on this map. Cited by 7 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07230587 phase3not yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Randomized, Double-Blind, Placebo-Controlled Study to Evaluate the Long-Term Efficacy of Butylphthalide in Patients With Minor Acute Ischemic Stroke (BLESS)

TypeinterventionalSponsorPeking Union Medical College HospitalRan2025 to 2028Enrolled1,200ConditionsIschemic Stroke, Minor StrokeArmsButylphthalide, Placebo
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Zefeng TanDepartment of Neurology, the First Affiliated Hospital, Jinan University, Guangzhou, China.
Yin ZhaoDepartment of Neurology, the First Affiliated Hospital, Jinan University, Guangzhou, China.
Wanyong YangDepartment of Neurology, the First Affiliated Hospital, Jinan University, Guangzhou, China.
Shenwen HeDepartment of Neurology, Shun De Hospital of Jinan University, Guangzhou, China.
Yan DingDepartment of Neurology, the First Affiliated Hospital, Jinan University, Guangzhou, China.
Anding XuDepartment of Neurology, the First Affiliated Hospital, Jinan University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

dl-3-n-butylphthalideefficacyminor strokemodified rankin scalenon-disablingTIA

Identifiers

PMID34630292
PMCPMC8492907

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.