ArticleFrontiers in physiology2021
A Phase Defect Framework for the Analysis of Cardiac Arrhythmia Patterns.
Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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5 citing papers in PubMed, 0 citations in OpenAlex.
- Analysis of complex excitation patterns using Feynman-like diagrams.Scientific reports · 2024Article
- The Ithildin library for efficient numerical solution of anisotropic reaction-diffusion problems in excitable media.PloS one · 2024Article
- A comprehensive framework for evaluation of high pacing frequency and arrhythmic optical mapping signals.Frontiers in physiology · 2023Article
- Impact of electrode orientation, myocardial wall thickness, and myofiber direction on intracardiac electrograms: numerical modeling and analytical solutions.Frontiers in physiology · 2023Article
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6 authors at 2 institutions in 2 countries.
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Abstract
During cardiac arrhythmias, dynamical patterns of electrical activation form and evolve, which are of interest to understand and cure heart rhythm disorders. The analysis of these patterns is commonly performed by calculating the local activation phase and searching for phase singularities (PSs), i.e., points around which all phases are present. Here we propose an alternative framework, which focuses on phase defect lines (PDLs) and surfaces (PDSs) as more general mechanisms, which include PSs as a specific case. The proposed framework enables two conceptual unifications: between the local activation time and phase description, and between conduction block lines and the central regions of linear-core rotors. A simple PDL detection method is proposed and applied to data from simulations and optical mapping experiments. Our analysis of ventricular tachycardia in rabbit hearts (
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