ArticleFrontiers in physiology2021
What Is Moderate to Vigorous Exercise Intensity?
Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 87 papers, 13 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Activity Levels Amongst Elderly Patients With Symptomatic Lumbar Spinal Stenosis Before and After Decompressive Surgery
Low Systemic/High Local Exercise Load in Pediatric Sickle Cell Disease
Who cites it
87 citing papers in PubMed, 13 syntheses or guidelines pooled it.
- Physical Activity Levels of Early Childhood Educators: A Systematic Review and Meta-Analysis.Child: care, health and development · 2026Pooled it
- Therapeutic and Preventive Role of Integrated Moderate-to-Vigorous Recreational Activity Programs in Type 2 Diabetes Care: A Systematic Review and Meta-Analysis.Advances in therapy · 2026Pooled it
- Pooled it
- National Heart Center/Saudi Heart Association 2025 Guidelines for Cardiovascular Diseases Prevention and Risk Assessment.Saudi medical journal · 2026Guideline
- Comparative efficacy of different scoliosis-specific exercise protocols on cobb angle in adolescent idiopathic scoliosis: a network meta-analysis.Frontiers in sports and active living · 2026Pooled it
- Exercise prescription to improve executive functioning in children and adolescents with attention deficit hyperactivity disorder: a network meta-analysis.Frontiers in psychiatry · 2026Pooled it
- The global scientific evolution of cardiopulmonary performance and threshold research in sports sciences during 2010-2025: a comparative bibliometric analysis based on web of science and scopus.Frontiers in research metrics and analytics · 2026Pooled it
- Pooled it
- The effectiveness of exercise interventions targeting sleep in older adults with cognitive impairment or Alzheimer's disease and related dementias (AD/ADRD): A systematic review and meta-analysis.Journal of sleep research · 2024Pooled it
- The Effects of Exercise-Based Injury Prevention Programmes on Injury Risk in Adult Recreational Athletes: A Systematic Review and Meta-Analysis.Sports medicine (Auckland, N.Z.) · 2024Pooled it
- Pooled it
- A new perspective on special effective interventions for metabolic syndrome risk factors: a systematic review and meta-analysis.Frontiers in public health · 2023Pooled it
- The optimal exercise modality and intensity for hemodialysis patients incorporating Bayesian network meta-analysis and systematic review.Frontiers in physiology · 2022Pooled it
- Quantifying Exercise Intensity to Predict Changes in Walking Capacity in Individuals with Chronic Stroke.Archives of physical medicine and rehabilitation · 2026Trial
- The recovery effect of acute aerobic exercise and music intervention on working memory under mental fatigue.Experimental brain research · 2025Trial
- Effects of an Acute High Dose of Caffeine on Physiological Responses and Performance During a Strength-Focused CrossFitNutrients · 2025Trial
- Moderate-to-Vigorous Physical Activity, Muscle Function, and Contemporary Sarcopenia Definitions in Older Adults With HIV.Journal of acquired immune deficiency syndromes (1999) · 2026Article
- Estimating Exercise Intensity Using Heart Rate Methods in Children and Young Adults with Pulmonary Hypertension.Pediatric cardiology · 2026Article
- Validation of aerobic threshold assessment using a sweat lactate sensor during arm crank exercise by healthy adults.Physiological reports · 2026Article
- Standardizing moderate- and vigorous-intensity exercise doses by physiological strain: an exploratory randomized cross-over study.European journal of applied physiology · 2026Article
27 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A variety of health benefits associated with physical activity depends upon the frequency, intensity, duration, and type of exercise. Intensity of exercise is the most elusive of these elements and yet has important implications for the health benefits and particularly cardiovascular outcomes elicited by regular physical activity. Authorities recommend that we obtain 150min of moderate to vigorous intensity physical activity (MVPA) each week. The current descriptions of moderate to vigorous intensity are not sufficient, and we wish to enhance understanding of MVPA by recognition of important boundaries that define these intensities. There are two key thresholds identified in incremental tests: ventilatory and lactate thresholds 1 and 2, which reflect boundaries related to individualized disturbance to homeostasis that are appropriate for prescribing exercise. VT2 and LT2 correspond with critical power/speed and respiratory compensation point. Moderate intensity physical activity approaches VT1 and LT1 and vigorous intensity physical activity is between the two thresholds (1 and 2). The common practice of prescribing exercise at a fixed metabolic rate (# of METs) or percentage of maximal heart rate or of maximal oxygen uptake (V̇O
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.