Evidence map›Paper›PMID 34630112›Full record

ReviewFrontiers in pharmacology2021

Molecular Basis of Prostate Cancer and Natural Products as Potential Chemotherapeutic and Chemopreventive Agents.

Bingke Bai, Qianbo Chen, Rui Jing, Xuhui He, Hongrui Wang, Yanfei Ban, Qi Ye, Weiheng Xu, Chengjian Zheng

Abstract readReview
In one paragraph

Review in Frontiers in pharmacology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. New prospects of cancer therapy based on pyroptosis and pyroptosis inducers.Apoptosis : an international journal on programmed cell death · 2024
    Review
  13. Review
  14. Review
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bingke BaiDepartment of Chinese Medicine Authentication, School of Pharmacy, Second Military Medical University, Shanghai, China.
Qianbo ChenDepartment of Anesthesiology, Shanghai Eastern Hepatobiliary Surgery Hospital, Shanghai, China.
Rui JingDepartment of Chinese Medicine Authentication, School of Pharmacy, Second Military Medical University, Shanghai, China.
Xuhui HeDepartment of Chinese Medicine Authentication, School of Pharmacy, Second Military Medical University, Shanghai, China.
Hongrui WangDepartment of Chinese Medicine Authentication, School of Pharmacy, Second Military Medical University, Shanghai, China.
Yanfei BanDepartment of Chinese Medicine Authentication, School of Pharmacy, Second Military Medical University, Shanghai, China.
Qi YeDepartment of Biological Science, College of Life Science, Fujian Agriculture and Forestry University, Fuzhou, China.
Weiheng XuDepartment of Biochemical Pharmacy, School of Pharmacy, Second Military Medical University, Shanghai, China.
Chengjian ZhengDepartment of Chinese Medicine Authentication, School of Pharmacy, Second Military Medical University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Prostate cancer is the second most common malignant cancer in males. It involves a complex process driven by diverse molecular pathways that closely related to the survival, apoptosis, metabolic and metastatic characteristics of aggressive cancer. Prostate cancer can be categorized into androgen dependent prostate cancer and castration-resistant prostate cancer and cure remains elusive due to the developed resistance of the disease. Natural compounds represent an extraordinary resource of structural scaffolds with high diversity that can offer promising chemical agents for making prostate cancer less devastating and curable. Herein, those natural compounds of different origins and structures with potential cytotoxicity and/or

Indexed as

androgen receptorapoptosismechanismnatural compoundsprostate cancer

Identifiers

PMID34630112
PMCPMC8495205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.