ArticleFrontiers in behavioral neuroscience2021
Measuring Behavior in the Home Cage: Study Design, Applications, Challenges, and Perspectives.
Article in Frontiers in behavioral neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 59 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
59 citing papers in PubMed, 103 citations in OpenAlex.
- SqueakPose Studio, an end-to-end platform for pose estimation and real-time edge-AI deployment.eLife · 2026Article
- Strategies for Optimizing Genetic Mouse Models to Enhance the Understanding of Parkinson's Disease.Biomedicines · 2026Review
- Integrating supervised and unsupervised machine learning for behavior segmentation reveals latent frailty signatures and improves aging clocks in isogenic and outbred mice.bioRxiv : the preprint server for biology · 2026Article
- Challenges and expectations on the use of automated home cage monitoring for advancing laboratory animal care and welfare.Laboratory animals · 2026Article
- SqueakPose Studio: An end-to-end platform for pose estimation and real-time edge-AI deployment.bioRxiv : the preprint server for biology · 2026Article
- Gender-Specific Behavior Reductions in Spontaneous Locomotive and Rearing in a Rat Model of Paclitaxel-Induced Peripheral Neuropathy: A Pilot Study.Journal of pain research · 2026Article
- Effects of Cage Change and Nest Transfer on Artificial Intelligence-Measured Behaviors in Male C57BL/6 Mice.Journal of the American Association for Laboratory Animal Science : JAALAS · 2026Article
- Effect of the Icelandic Mutation APPBiomolecules · 2025Article
- Robust noninvasive detection of hyperglycemia in mouse models of metabolic dysregulation using the novel Urination Index biomarker.Lab animal · 2025Article
- Establishment of a second-generation transgenic marmoset with germline transmission that models polyglutamine disease.Disease models & mechanisms · 2025Article
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- Automated home-cage-like monitoring for assessing innate behaviors in a murine hangover model.Scientific reports · 2025Article
- Mineralocorticoid receptor deletion alters spontaneous behavior in an automated home-cage monitoring apparatus.Hormones and behavior · 2025Article
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- A circadian behavioral analysis suite for real-time classification of daily rhythms in complex behaviors.Cell reports methods · 2025Article
- Time Perception Test in IntelliCage System for Preclinical Study: Linking Depression and Serotonergic Modulation.Diagnostics (Basel, Switzerland) · 2025Article
- The SnackerTracker: A novel home-cage monitoring device for measuring food-intake and food-seeking behaviour in mice.Wellcome open research · 2025Article
- Characterization of alterations in spontaneous behaviors in a rat model of neuropathic pain - new outcome measures for pain evaluation?Frontiers in behavioral neuroscience · 2025Article
- Behavioral characterization of triple-hit schizophrenia-like Lisket rats derived from the Long Evans strain through acute and chronic behavioral tests.Frontiers in psychiatry · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
29 authors at 16 institutions in 6 countries.
Funding
Abstract
The reproducibility crisis (or replication crisis) in biomedical research is a particularly existential and under-addressed issue in the field of behavioral neuroscience, where, in spite of efforts to standardize testing and assay protocols, several known and unknown sources of confounding environmental factors add to variance. Human interference is a major contributor to variability both within and across laboratories, as well as novelty-induced anxiety. Attempts to reduce human interference and to measure more "natural" behaviors in subjects has led to the development of automated home-cage monitoring systems. These systems enable prolonged and longitudinal recordings, and provide large continuous measures of spontaneous behavior that can be analyzed across multiple time scales. In this review, a diverse team of neuroscientists and product developers share their experiences using such an automated monitoring system that combines Noldus PhenoTyper
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.