Evidence map›Paper›PMID 34630049›Full record

ArticleFrontiers in neuroanatomy2021

Multi-Scale Light-Sheet Fluorescence Microscopy for Fast Whole Brain Imaging.

Zhouzhou Zhang, Xiao Yao, Xinxin Yin, Zhangcan Ding, Tianyi Huang, Yan Huo, Runan Ji, Hanchuan Peng, Zengcai V Guo

Abstract read
In one paragraph

Article in Frontiers in neuroanatomy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhouzhou ZhangSchool of Medicine, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing, China.
Xiao YaoSchool of Medicine, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing, China.
Xinxin YinSchool of Medicine, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing, China.
Zhangcan DingSEU-Allen Joint Center, Institute for Brain and Intelligence, Southeast University, Nanjing, China.
Tianyi HuangSchool of Medicine, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing, China.
Yan HuoSchool of Medicine, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing, China.
Runan JiSchool of Medicine, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing, China.
Hanchuan PengSEU-Allen Joint Center, Institute for Brain and Intelligence, Southeast University, Nanjing, China.
Zengcai V GuoSchool of Medicine, IDG/McGovern Institute for Brain Research, Tsinghua University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Whole-brain imaging has become an increasingly important approach to investigate neural structures, such as somata distribution, dendritic morphology, and axonal projection patterns. Different structures require whole-brain imaging at different resolutions. Thus, it is highly desirable to perform whole-brain imaging at multiple scales. Imaging a complete mammalian brain at synaptic resolution is especially challenging, as it requires continuous imaging from days to weeks because of the large number of voxels to sample, and it is difficult to acquire a constant quality of imaging because of light scattering during

Indexed as

electrode localizationlight-sheet microscopymulti-scale imagingsingle neuron morphologywhole brain imaging

Identifiers

PMID34630049
PMCPMC8497830

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.