Evidence map›Paper›PMID 34630045›Full record

ArticleFrontiers in cellular neuroscience2021

Evidence That

Ruyi Mei, Linyu Huang, Mengyuan Wu, Chunxia Jiang, Aifen Yang, Huaping Tao, Kang Zheng, Junlin Yang, Wanhua Shen, Xianjun Chen and 2 more

Abstract read
In one paragraph

Article in Frontiers in cellular neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ruyi MeiCollege of Life Sciences, Zhejiang University, Hangzhou, China.
Linyu HuangZhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Institute of Developmental and Regenerative Biology, Hangzhou Normal University, Hangzhou, China.
Mengyuan WuZhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Institute of Developmental and Regenerative Biology, Hangzhou Normal University, Hangzhou, China.
Chunxia JiangCollege of Life Sciences, Zhejiang University, Hangzhou, China.
Aifen YangZhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Institute of Developmental and Regenerative Biology, Hangzhou Normal University, Hangzhou, China.
Huaping TaoZhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Institute of Developmental and Regenerative Biology, Hangzhou Normal University, Hangzhou, China.
Kang ZhengZhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Institute of Developmental and Regenerative Biology, Hangzhou Normal University, Hangzhou, China.
Junlin YangZhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Institute of Developmental and Regenerative Biology, Hangzhou Normal University, Hangzhou, China.
Wanhua ShenZhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Institute of Developmental and Regenerative Biology, Hangzhou Normal University, Hangzhou, China.
Xianjun ChenDepartment of Physiology, Research Center of Neuroscience, Chongqing Medical University, Chongqing, China.
Xiaofeng ZhaoZhejiang Key Laboratory of Organ Development and Regeneration, College of Life and Environmental Sciences, Institute of Developmental and Regenerative Biology, Hangzhou Normal University, Hangzhou, China.
Mengsheng QiuCollege of Life Sciences, Zhejiang University, Hangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myelination of neuronal axons in the central nervous system (CNS) by oligodendrocytes (OLs) enables rapid saltatory conductance and axonal integrity, which are crucial for normal brain functioning. Previous studies suggested that different subtypes of oligodendrocytes in the CNS form different types of myelin determined by the diameter of axons in the unit. However, the molecular mechanisms underlying the developmental association of different types of oligodendrocytes with different fiber sizes remain elusive. In the present study, we present the evidence that the intracellular Ca

Indexed as

axon diameterconduction velocityITPR2myelinationoligodendrocyte

Identifiers

PMID34630045
PMCPMC8492996

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.