ArticleFrontiers in neuroscience2021
Aerobic Exercise Attenuates Pain Sensitivity: An Event-Related Potential Study.
Article in Frontiers in neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 3 syntheses or guidelines pooled it, 33 citations in OpenAlex.
- Comparative effectiveness of exercise interventions for primary dysmenorrhea: a systematic review and network meta-analysis.BMC women's health · 2024Pooled it
- Exercise for Neuropathic Pain: A Systematic Review and Expert Consensus.Frontiers in medicine · 2021Pooled it
- Top 100 Most-Cited Papers in Neuropathic Pain From 2000 to 2020: A Bibliometric Study.Frontiers in neurology · 2021Pooled it
- Physiological and autonomic responses to intermittent low-lung-volume apnoea and pain sensitivity: A randomized controlled pilot trial.Experimental physiology · 2026Trial
- High-Definition Transcranial Direct Current Stimulation Enhances Exercise-Induced Hypoalgesia in Healthy Individuals: An fNIRS Study.Brain and behavior · 2025Trial
- Hypoalgesic effects, safety, and feasibility of a 6-minute high-lung-volume static apnea intervention.The Korean journal of pain · 2026Article
- Acute Effects of Low-Intensity Blood-Flow-Restricted Walking on Pain Sensitivity, Joint Range of Motion, and Myofascial Stiffness in Healthy Adults.Journal of clinical medicine · 2026Article
- Exploring Predictors of Self-Perceived Cardiorespiratory Fitness ≥ 5 Years Beyond Breast Cancer Diagnosis: A Cross-Sectional Study.Healthcare (Basel, Switzerland) · 2025Article
- Impact of electrical muscle stimulation-induced muscle contractions on endogenous pain modulatory system: a quantitative sensory testing evaluation.BMC musculoskeletal disorders · 2024Article
- Effects of Apnea-Induced Hypoxia on Hypoalgesia in Healthy Subjects.Sports (Basel, Switzerland) · 2024Article
- Physical exercise for brain plasticity promotion an overview of the underlying oscillatory mechanism.Frontiers in neuroscience · 2024Review
- The Rehabilitation-Related Effects on the Fear, Pain, and Disability of Patients With Lumbar Fusion Surgery: A Systematic Review and Meta-Analysis.Neurospine · 2023Article
- Effect and mechanisms of exercise for complex regional pain syndrome.Frontiers in molecular neuroscience · 2023Review
- Trends of Low Back Pain Research in Older and Working-Age Adults from 1993 to 2023: A Bibliometric Analysis.Journal of pain research · 2023Review
- Response to experimental cold-induced pain discloses a resistant category among endurance athletes, with a distinct profile of pain-related behavior and GABAergic EEG markers: a case-control preliminary study.Frontiers in neuroscience · 2023Article
- Effect of Tai Chi Quan on the Pressure Pain Thresholds of Lower Back Muscles in Healthy Women.Journal of pain research · 2022Article
- Differences and Correlations of Anxiety, Sleep Quality, and Pressure-Pain Threshold between Patients with Chronic Low Back Pain and Asymptomatic People.Pain research & management · 2022Article
- Non-invasive Brain Stimulation for Central Neuropathic Pain.Frontiers in molecular neuroscience · 2022Review
- Exercise for Osteoarthritis: A Literature Review of Pathology and Mechanism.Frontiers in aging neuroscience · 2022Review
- The Last Decade Publications on Diabetic Peripheral Neuropathic Pain: A Bibliometric Analysis.Frontiers in molecular neuroscience · 2022Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In this study, electroencephalography (EEG) was utilized to explore the neurophysiological mechanisms of aerobic exercise-induced hypoalgesia (EIH) and provide a theoretical basis for the application of aerobic exercise in pain assessment and treatment. Forty-five healthy subjects were randomly divided into moderate-intensity aerobic exercise [70% heart rate reserve (HRR)], low-intensity aerobic exercise (50% HRR), or control groups (sitting). Aerobic exercise was performed with cycling. Pressure pain threshold (PPT), heat pain threshold (HPT), event-related potential (ERP) induced by contact heat stimulus and pain scoring were measured before and after the intervention. We found that moderate-intensity aerobic exercise can increase the PPT (rectus femoris:
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.