Evidence map›Paper›PMID 34629908›Full record

ArticleInternational medical case reports journal2021

Spontaneous Regression of Merkel Cell Carcinoma: Case Report.

Branislav Bystricky, Filip Kohutek, Zuzana Miklatkova, Tomas Sedlacek, Viliam Gal, Regina Lohajova Behulova

Open access · goldAbstract readCase Reports
In one paragraph

Article in International medical case reports journal, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Branislav BystrickyOncology Department, Faculty Hospital Trencin, Trencin, Slovakia and Faculty of Healthcare, Alexander Dubcek University of Trencin, Trencin, Slovakia.ORCID 0000-0002-9622-8557
Filip KohutekOncology Department, Faculty Hospital Trencin, Trencin, Slovakia.ORCID 0000-0001-6169-0680
Zuzana MiklatkovaOncology Department, Faculty Hospital Trencin, Trencin, Slovakia.
Tomas SedlacekMedicyt Trencin, Trencin, Slovakia.
Viliam GalUnilabs Slovakia, Bratislava, Slovakia.ORCID 0000-0001-9435-7825
Regina Lohajova BehulovaDepartment of Clinical Genetics, St. Elisabeth Cancer Institute, Bratislava, Slovakia.
Vysoká škola manažmentu, City University of Seattle · SKNational Bank of Slovakia · SKVysoká Škola Zdravotníctva a Sociálnej Práce sv. Alžbety · SK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Merkel cell carcinoma (MCC) is a rare skin neuroendocrine tumor presumably arising from Merkel cells in the basal layer of epidermis. It is an aggressive tumor predominantly found on the head and neck area of elderly people, with a mortality rate around 41% for all stages. Complete spontaneous regression of MCC is seldom observed, mostly in elderly women. We describe complete spontaneous regression of large, histologically confirmed MCC in an elderly woman after biopsy, which occurred incidentally, while waiting for radical surgery with skin flap. Next-generation sequencing with SOPHiA Solid Tumor Plus Solution did not reveal any relevant gene mutations or rearrangements. An update of literature for these very rare cases is provided.

Indexed as

next-generation sequencingskin neuroendocrine tumorzygomatic region

Identifiers

PMID34629908
PMCPMC8495228
OpenAlexW3203168122

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.