Evidence map›Paper›PMID 34629815›Full record

ArticleWorld journal of gastroenterology2021

Fluorescent cholangiography: An up-to-date overview twelve years after the first clinical application.

Antonio Pesce, Gaetano Piccolo, Francesca Lecchi, Nicolò Fabbri, Michele Diana, Carlo Vittorio Feo

3 registry-linked trialsAbstract readEditorial
In one paragraph

Article in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05419947 phase4completednot on this mapstarted 2022, after this paper: background citation

Randomized Clinical Trial for the Optimization of Indocyanine Green Administration in Near-infrared Fluorescent Cholangiography During Laparoscopic Cholecystectomy.

TypeinterventionalSponsorFundación Instituto de Estudios de Ciencias de la Salud de Castilla y LeónRan2022 to 2023Enrolled200ConditionsLaparoscopic CholecystectomyArmsVERDYE powder for solution for injection 25 mg
NCT05709548 phase4unknown statusnot on this mapstarted 2023, after this paper: background citation

INDURG TRIAL: A Randomized Controlled Trial Using Indocyanine Green During Cholecystectomy in Acute Cholecystitis

TypeinterventionalSponsorCorporacion Parc TauliRan2023 to 2025Enrolled440ConditionsAcute Cholecystitis, Bile Duct InjuryArmsIndocyanine green
NCT06573021 completednot on this mapstarted 2023, after this paper: background citation

The Role of Fluorescent Cholangiography to Improve Operative Safety in Different Severity Degree of Acute Cholecystitis During Emergency Laparoscopic Cholecystectomy.

Typeobservational_patient_registrySponsorUniversity Hospital of FerraraRan2023 to 2024Enrolled81ConditionsAcute CholecystitisArmsNear-infrared fluorescent cholangiography
3 · Its place in the literature

Who cites it

25 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Trial
  4. Trial
  5. A History of Cholecystectomy.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2026
    Article
  6. Review
  7. Review
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Laparoscopic cholecystectomy for duplication of the gallbladder: A case report.International journal of surgery case reports · 2025
    Article
  14. Article
  15. Article
  16. Review
  17. Observational
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Antonio PesceDepartment of Surgery, Section of General Surgery, Ospedale del Delta, Azienda USL of Ferrara, University of Ferrara, Ferrara 44023, Italy. antonio.pesce@ausl.fe.it.
Gaetano PiccoloDepartment of Health Sciences, University of Milan, Unit of Hepato-Bilio-Pancreatic and Digestive Surgery, San Paolo Hospital, Milano 20142, Italy.
Francesca LecchiDepartment of Health Sciences, University of Milan, Unit of Hepato-Bilio-Pancreatic and Digestive Surgery, San Paolo Hospital, Milano 20142, Italy.
Nicolò FabbriDepartment of Surgery, Section of General Surgery, Ospedale del Delta, Azienda USL of Ferrara, University of Ferrara, Ferrara 44023, Italy.
Michele DianaDepartment of General, Digestive and Endocrine Surgery, University Hospital of Strasbourg, IRCAD, Research Institute Against Digestive Cancer, ICUBE lab, PHOTONICS for Health, University of Strasbourg, Strasbourg Cedex F-67091, France.
Carlo Vittorio FeoDepartment of Surgery, Section of General Surgery, Ospedale del Delta, Azienda USL of Ferrara, University of Ferrara, Ferrara 44023, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Laparoscopic cholecystectomy (LC) is one of the most frequently performed gastrointestinal surgeries worldwide. Bile duct injury (BDI) represents the most serious complication of LC, with an incidence of 0.3%-0.7%, resulting in significant perioperative morbidity and mortality, impaired quality of life, and high rates of subsequent medico-legal litigation. In most cases, the primary cause of BDI is the misinterpretation of biliary anatomy, leading to unexpected biliary lesions. Near-infrared fluorescent cholangiography is widely spreading in clinical practice to delineate biliary anatomy during LC in elective and emergency settings. The primary aim of this article was to perform an up-to-date overview of the evolution of this method 12 years after the first clinical application in 2009 and to highlight all advantages and current limitations according to the available scientific evidence.

Indexed as

Bile Duct DiseasesCholecystectomy, LaparoscopicCholangiographyColoring AgentsHumansQuality of LifeColoring AgentsBile duct injuryBiliary anatomyFluorescent cholangiographyIndocyanine greenLaparoscopic cholecystectomy

Identifiers

PMID34629815
PMCPMC8476339

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.