Evidence map›Paper›PMID 34629792›Full record

ReviewWorld journal of gastroenterology2021

Liver disorders in COVID-19, nutritional approaches and the use of phytochemicals.

Nancy Vargas-Mendoza, Jazmín García-Machorro, Marcelo Angeles-Valencia, Marlet Martínez-Archundia, Eduardo Osiris Madrigal-Santillán, Ángel Morales-González, Liliana Anguiano-Robledo, José A Morales-González

Open access · bronzeAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Targeting macro- and micro-nutrient regulation of HNeurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Nancy Vargas-MendozaLaboratorio de Medicina de Conservacion, Instituto Politécnico Nacional, México 11340, Mexico.
Jazmín García-MachorroLaboratorio de Medicina de Conservacion, Instituto Politécnico Nacional, México 11340, Mexico.
Marcelo Angeles-ValenciaLaboratorio de Medicina de Conservacion, Instituto Politécnico Nacional, México 11340, Mexico.
Marlet Martínez-ArchundiaLaboratorio de Diseño y Desarrollo de Nuevos Fármacos e Innovación Biotécnológica, Instituto Politécnico Nacional, México 11340, Mexico.
Eduardo Osiris Madrigal-SantillánEscuela Superior de Medicina, Instituto Politécnico Nacional, México 11340, Mexico.
Ángel Morales-GonzálezEscuela Superior de Cómputo, Instituto Politécnico Nacional, México 07738, Mexico.
Liliana Anguiano-RobledoLaboratorio de Farmacología Molecular, Instituto Politécnico Nacional, México 11340, Mexico.
José A Morales-GonzálezLaboratorio Medicina de Conservación, Escuela Superior de Medicina, Instituto Politécnico Nacional, México 11340, Mexico. jmorales101@yahoo.com.mx.
Instituto Politécnico Nacional · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus disease 2019 (COVID-19), which is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2), has affected millions of people globally. It was declared a pandemic by the World Health Organization in March 2020. The hyperinflammatory response to the entry of SARS-CoV-2 into the host through angiotensin-converting enzyme 2 is the result of a "cytokine storm" and the high oxidative stress responsible for the associated symptomatology. Not only respiratory symptoms are reported, but gastrointestinal symptoms (diarrhea, vomiting, and nausea) and liver abnormalities (high levels of aspartate aminotransferase, alanine aminotransferase transaminases, and bilirubin) are observed in at least 30% of patients. Reduced food intake and a delay in medical services may lead to malnutrition, which increases mortality and poor outcomes. This review provides some strategies to identify malnutrition and establishes nutritional approaches for the management of COVID-19 and liver injury, taking energy and nutrient requirements and their impact on the immune response into account. The roles of certain phytochemicals in the prevention of the disease or as promising target drugs in the treatment of this disease are also considered.

Indexed as

COVID-19Peptidyl-Dipeptidase AHumansLiverPhytochemicalsSARS-CoV-2Peptidyl-Dipeptidase APhytochemicalsCOVID-19InfectionLiverNutrition therapyPhytochemicals

Identifiers

PMID34629792
PMCPMC8473593
OpenAlexW3200194862

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.