Evidence map›Paper›PMID 34629733›Full record

ArticleJournal of toxicologic pathology2021

Safety and efficacy of sFilm-FS, a novel biodegradable fibrin sealant, in Göttingen minipigs.

Yuval Ramot, Michal Steiner, Yossi Lavie, Nati Ezov, Orgad Laub, Eran Cohen, Yotam Schwartz, Abraham Nyska

Open access · diamondAbstract read
In one paragraph

Article in Journal of toxicologic pathology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Yuval RamotFaculty of Medicine, Hebrew University of Jerusalem, Jerusalem, Israel.
Michal SteinerEnvigo CRS (Israel), Ness Ziona, 7403617, Israel.
Yossi LavieEnvigo CRS (Israel), Ness Ziona, 7403617, Israel.
Nati EzovEnvigo CRS (Israel), Ness Ziona, 7403617, Israel.
Orgad LaubSealantium Medical, Afek Industrial Area, P.O.B. 11817, Rosh Ha'Ayin, 4809239, Israel.
Eran CohenSealantium Medical, Afek Industrial Area, P.O.B. 11817, Rosh Ha'Ayin, 4809239, Israel.
Yotam SchwartzSealantium Medical, Afek Industrial Area, P.O.B. 11817, Rosh Ha'Ayin, 4809239, Israel.
Abraham NyskaConsultant in Toxicologic Pathology, Yehuda HaMaccabi 31, floor 5, Tel Aviv, 6200515, Israel.
Israel Institute for Biological Research · ILHadassah Medical Center · ILVascular Biogenics (Israel) · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bleeding during surgical procedures is a common complication. Therefore, hemostatic agents have been developed to control bleeding, and fibrin sealants have several benefits. sFilm-FS is a novel fibrin sealant that comprises a biodegradable co-polymeric film embedded with human fibrinogen and thrombin. Herein, the safety and efficacy of sFilm-FS were compared using a liver and spleen puncture model of Göttingen minipigs with those of the standard hemostatic techniques (control animals) and EVARREST

Indexed as

animal modelsbiodegradabilitybiodegradable materialsbleedinghemostasislocal tolerability

Identifiers

PMID34629733
PMCPMC8484930
OpenAlexW3177959110

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.