Evidence map›Paper›PMID 34629710›Full record

ReviewSeminars in interventional radiology2021

Contemporary Algorithm for the Management of Hepatocellular Carcinoma in 2021: The Northwestern Approach.

Adam Swersky, Laura Kulik, Aparna Kalyan, Karen Grace, Juan Carlos Caicedo, Robert J Lewandowski, Riad Salem

Abstract readReview
In one paragraph

Review in Seminars in interventional radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Local-Regional Treatment of Hepatocellular Carcinoma: A Primer for Radiologists.Radiographics : a review publication of the Radiological Society of North America, Inc · 2022
    Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adam SwerskySection of Interventional Radiology, Department of Radiology, Northwestern Feinberg School of Medicine, Chicago, Illinois.
Laura KulikDivision of Hepatology, Department of Medicine, Northwestern Feinberg School of Medicine, Chicago, Illinois.
Aparna KalyanDivision of Medical Oncology, Department of Medicine, Northwestern Feinberg School of Medicine, Chicago, Illinois.
Karen GraceSection of Interventional Radiology, Department of Radiology, Northwestern Feinberg School of Medicine, Chicago, Illinois.
Juan Carlos CaicedoDivision of Transplantation, Department of Surgery, Northwestern Feinberg School of Medicine, Chicago, Illinois.
Robert J LewandowskiSection of Interventional Radiology, Department of Radiology, Northwestern Feinberg School of Medicine, Chicago, Illinois.
Riad SalemSection of Interventional Radiology, Department of Radiology, Northwestern Feinberg School of Medicine, Chicago, Illinois.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hepatocellular carcinoma (HCC) is the most common primary liver cancer and a major cause of cancer-related morbidity and mortality around the world. Frequently, concurrent liver dysfunction and variations in tumor burden make it difficult to design effective and standardized treatment pathways. Contemporary treatment guidelines designed for an era of personalized medicine should consider these features in a more clinically meaningful way to improve outcomes for patients across the HCC spectrum. Given the heterogeneity of HCC, we propose a detailed clinical algorithm for selecting optimal treatment using an evidence-based and practical approach, incorporating liver function, tumor burden, the extent of disease, and ultimate treatment intent, with the goal of individualizing clinical decision making.

Indexed as

downstaginginterventional radiologyradioembolizationsurvivaltransplantationyttrium-90

Identifiers

PMID34629710
PMCPMC8497077

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.