Evidence map›Paper›PMID 34629692›Full record

ArticleArchivos de la Sociedad Espanola de Oftalmologia2022

[Hypochlorous acid as an antiseptic in the care of patients with suspected COVID-19 infection].

M Gessa-Sorroche, I Relimpio-López, S García-Delpech, J M Benítez-Del-Castillo

Open access · greenAbstract readEnglish Abstract
In one paragraph

Article in Archivos de la Sociedad Espanola de Oftalmologia, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 80% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

M Gessa-SorrocheUnidad de Córnea y Superficie Ocular, Servicio de Oftalmología, Hospital Universitario Virgen Macarena, Clínica Miranza Virgen de Luján, Sevilla, España.
I Relimpio-LópezUnidad de Retina quirúrgica, Servicio de Oftalmología, Hospital Universitario Virgen Macarena, Clínica Amiras, Hospital Viamed Santa Ángela de la Cruz, Sevilla, España.
S García-DelpechClínica Aiken, Valencia, España.
J M Benítez-Del-CastilloUnidad de Córnea y Superficie Ocular, Servicio de Oftalmología, Hospital Clínico San Carlos, Universidad Complutense, Instituto Castroviejo, Clínica Rementería, Madrid, España.
Hospital Universitario Virgen Macarena · ESHospital Clínico San Carlos · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe SARS-CoV-2 virus, which causes COVID-19 disease, is transmitted by aerosols or by contact with infected surfaces. The route of entry to the body is through the nasal, oral or conjunctival mucosa. Health workers must use effective protection measures against the entry of the virus into mucous membranes, both physical and antiseptic filters. There is an antiseptic used in Ophthalmology that we believe could have virucidal action against the SARS-CoV-2 virus, formulated based on 0.01% hypochlorous acid.

methodsAn exhaustive search has been carried out in the databases of Pubmed and Web of Science to identify relevant articles on the virucidal activity of hypochlorous acid in different concentrations until October 4, 2020.

resultsThere is evidence of the virucidal efficacy of 0.01% hypochlorous acid against SARS-CoV-2. According to the different scientific publications reviewed, hypochlorous acid has virucidal efficacy against different viruses, among them, SARS-CoV-2.

conclusionsThe 0.01% hypochlorous acid could act as an effective antiseptic against SARS-CoV-2, exerting a barrier on the mucosa to prevent COVID-19 infection. It can be used on the eyes, nose and mouth. We consider it necessary to assess its use in the protocol for patient health care in ophthalmology consultations, as well as to recommend its use to the general population to reduce viral load and / or prevent transmission of infection. Additional in vivo studies would be required to confirm its antiseptic action.

Indexed as

AntisepticConjunctivitisCOVID-19Hypochlorous acidSARS-CoV-2Virucidal

Identifiers

PMID34629692
PMCPMC8492602
OpenAlexW3203194338

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.