Evidence map›Paper›PMID 34629653›Full record

ReviewArchivos de bronconeumologia2021

[Thrombotic Risk and Covid-19: Review of Current Evidence for a Better Diagnostic and Therapeutic Approach].

Raquel López-Reyes, Grace Oscullo, David Jiménez, Irene Cano, Alberto García-Ortega

Open access · greenAbstract readEnglish AbstractReview
In one paragraph

Review in Archivos de bronconeumologia, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 19 citations in OpenAlex.

  1. Epidemiology of the COVID-19 pneumonia in a group of hospitals from Madrid-Spain during the full period of the State of Alarm HM cohort.Revista espanola de quimioterapia : publicacion oficial de la Sociedad Espanola de Quimioterapia · 2025
    Observational
  2. Review
  3. [Assessment of pulmonary embolism related to active SARS-CoV-2 infection in pregnant women.]Revista espanola de medicina nuclear e imagen molecular · 2022
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. [Enoxaparin dose associated with decreased risk of death in COVID-19].Revista medica del Instituto Mexicano del Seguro Social · 2022
    Observational
  11. Review
  12. Article
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Raquel López-ReyesServicio de Neumología, Hospital Universitario y Politécnico la Fe, Valencia, España.
Grace OsculloServicio de Neumología, Hospital Universitario y Politécnico la Fe, Valencia, España.
David JiménezServicio de Neumología. Hospital Ramón y Cajal (IRYCIS), Madrid, España.
Irene CanoServicio de Neumología. Hospital Ramón y Cajal (IRYCIS), Madrid, España.
Alberto García-OrtegaServicio de Neumología, Hospital Universitario y Politécnico la Fe, Valencia, España.
Hospital Universitari i Politècnic La Fe · ESCentro de Investigación Biomédica en Red de Enfermedades Respiratorias · ESInstituto Ramón y Cajal de Investigación Sanitaria · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The new SARS-CoV-2 coronavirus has created an unprecedented global health problem, resulting in more than 250,000 confirmed deaths. The disease produced by this virus, called Covid-19, presents with variable clinical manifestations, from practically asymptomatic patients with catarrhal processes to severe pneumonias that rapidly evolve to acute respiratory distress syndrome (ARDS) and multiorgan failure. In recent weeks, papers have been published describing coagulation disorders and arterial and venous thrombotic complications in these patients, mainly among those admitted to intensive care units. The infection triggers an immune response, which causes different inflammatory mediators to be released into the blood. These include cytokines, which interact with platelets and different coagulation proteins, and promote thrombogenesis. One of the most widely studied coagulation markers in Covid-19 is D-dimer (DD), raised levels of which have prognostic implications, although the best cut-off point for the diagnosis of venous thromboembolism (VTE) in this population has not been clarified, nor has its usefulness in determining the intensity of thromboprophylaxis required in these patients. Until sufficiently robust information (preferably from well-designed clinical trials) is available, the recommendations of clinical practice guidelines for the prophylaxis, diagnosis and treatment of VTE should be followed in Covid-19 patients.

Indexed as

AnticoagulationCovid-19Pulmonary embolismThrombosis

Identifiers

PMID34629653
PMCPMC7457904
OpenAlexW3081599654

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.