Evidence map›Paper›PMID 34629323›Full record

ArticleSexual medicine2021

Description of Vaginal Laxity and Prolapse and Correlation With Sexual Function (DeVeLoPS).

Allison Polland, Vi Duong, Rachel Furuya, Jocelyn J Fitzgerald, Haijun Wang, Aya Iwamoto, Sarah Bradley, Cheryl B Iglesia

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Sexual medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06872281 (A Randomized Controlled Trial Comparing Fractional Bipolar Radiofrequency Therapy VS Sham for Treatment of Vaginal Laxity in Premenopausal Women), which is not on this map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06872281 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

A Randomized Controlled Trial Comparing Fractional Bipolar Radiofrequency Therapy VS Sham for Treatment of Vaginal Laxity in Premenopausal Women

TypeinterventionalSponsorMahidol UniversityRan2025 to 2025Enrolled56ConditionsVaginal LaxityArmsFractional bipolar radiofrequency, Sham device
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 25 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 8 institutions in 1 country.

Allison PollandMaimonides Medical Center, Brooklyn, NY.
Vi DuongGeorgetown University School of Medicine/MedStar Health, Washington, DC; Massachussets General Hospital, Boston, MA. Electronic address: viduong414@gmail.com.
Rachel FuruyaDonald and Barbara Zucker School of Medicine at Hofstra/Northwell, New York, NY.
Jocelyn J FitzgeraldUniversity of Pittsburgh Medical Center, Pittsburgh, PA.
Haijun WangMedStar Health Research Institute.
Aya IwamotoUniversity of Iowa Hospitals and Clinics, Iowa City, IA.
Sarah BradleyMission Hospital, Ashville, NC.
Cheryl B IglesiaGeorgetown University School of Medicine/MedStar Health, Washington, DC.
Donald & Barbara Zucker School of Medicine at Hofstra/Northwell · USMaimonides Medical Center · USMassachusetts General Hospital · USMedStar Georgetown University Hospital · USMedStar Health · USMission Hospital · USUniversity of Iowa Hospitals and Clinics · USUniversity of Pittsburgh Medical Center · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionVaginal laxity (VL) is a sensation of vaginal looseness which may develop after pregnancy and vaginal delivery and may be affected by prior pelvic surgery, menopause and aging. Pelvic organ prolapse (POP) is a disorder in which pelvic organs descend from the normal position. VL has attracted recent attention due to the advent of energy-based treatments for this symptom.

aimTo determine the correlation between VL symptoms and physical exam findings of POP, specifically the introital measurement of genital hiatus.

methodsThis was a multi-center cross-sectional study of sexually active women over 18 years of age with a parity of one or greater. Subjects completed the Vaginal Laxity Questionnaire (VLQ), the Pelvic Floor Distress Inventory-20, and the Female Sexual Function Index (FSFI), and were asked if a sexual partner had commented on laxity. Subjects underwent pelvic exam, including the pelvic organ prolapse quantification (POP-Q). MAIN OUTCOMES MEASURES: Correlation between VL symptoms as measured by the VLQ and POP as measured by elements of the POP-Q.

resultsA total of 95 subjects with an average age was 54.3 ± 13.18 years were included. Sixty-three percent of patients were postmenopausal. The average VLQ score was 4.2 ± 1.35 and the average FSFI score was 23.42 out of 36. There was no significant correlation between VLQ score and POP or mid-vaginal caliber. Sensation of vaginal tightness was significantly associated with age (P=0.03) and menopausal status (P=0.04). Only 28% of partners commented on laxity and the majority commented on the vagina being tight (21%) rather than loose (7%).

conclusionVL was not correlated with physical exam findings quantifying POP or sexual function. This study emphasizes the need to develop a more standardized definition of VL and a better assessment tool for VL symptoms. Polland A, Duong V, Furuya R, et al. Description of Vaginal Laxity and Prolapse and Correlation With Sexual Function (DeVeLoPS). Sex Med 2021;9:100443.

Indexed as

Female Sexual Function IndexPelvic Floor Distress InventoryPOP-QVaginal LaxityVaginal Laxity Questionnaire

Identifiers

PMID34629323
PMCPMC8766263
OpenAlexW3206530025

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.